CHURC1 and ZNF581

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHURC1	ZNF581
Description		churchill domain containing 1	zinc finger protein 581
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		4 interacting genes: APP SERTAD1 ZBTB9 ZNF581	94 interacting genes: AP2M1 APOBEC3C APP ASB13 ATG9A BANP BOLA2 BOLA2B CALCOCO2 CARD10 CBY2 CCDC136 CCNDBP1 CHURC1 CNFN CYSRT1 DAZAP2 DOCK8 DVL2 DVL3 EFEMP2 ENKD1 ETFDH FAM90A1 FANCL FHL5 FSD2 GOLGA2 GOLGA6L9 GOPC GPSM3 HMBOX1 HNRNPC HNRNPF HSF2BP IKZF1 IL16 KDM1A KHDRBS2 KRT27 KRT34 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LNX1 LNX2 LZTS2 MDFI MGAT5B MTUS2 NBPF19 NID2 NOTCH2NLA NUDT22 PDE4DIP PLAGL2 PLEKHF2 PLSCR1 PNMA1 POU2AF1 PRKAB2 RBPMS RIMBP3C RSKR SDCBP2 SERTAD2 SMARCC1 SOX5 SPAG8 SPG21 SUV39H1 TEKT4 TMCC2 TRAF1 TRAF4 TRIM23 TRIM27 TRIM55 TRIM63 TRIP6 WWOX ZNF765 ZNF792
Entrez ID		91612	51545
HPRD ID		12262	15858
Ensembl ID		ENSG00000258289	ENSG00000171425
Uniprot IDs		Q8WUH1	Q9P0T4
PDB IDs		2JOX
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Axon Midline Choice Point Recognition Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of RNA Metabolic Process Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Nucleobase-containing Compound Metabolic Process Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding	Intermediate Filament Keratin Filament Identical Protein Binding Protein Binding CD4 Receptor Binding Transcription Coactivator Activity
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