TMEM229B and MMGT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM229B	MMGT1
Description		transmembrane protein 229B	membrane magnesium transporter 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Early Endosome Membrane EMC Complex
	Molecular Function	Protein Binding	Protein Binding Cobalt Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity
	Biological Process	Response To Bacterium Macrophage Activation	Monoatomic Cation Transport Cobalt Ion Transport Copper Ion Transport Iron Ion Transport Magnesium Ion Transport Iron Ion Transmembrane Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport
Pathways			Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Obesity-related traits ( 23251661) Parkinson's disease ( 25064009 28892059) Refractive error ( 32231278) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		43 interacting genes: ACBD5 AQP6 ARL13B BIK CD53 CD79A CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 GORAB GPX8 HSD17B13 ITGAM LHFPL5 MFF MGST3 MMGT1 MUC1 MYG1 NCR1 NEMP1 PANX1 PIGP PKMYT1 PVR REEP4 SEC22B SLC10A6 SLC39A2 SLC71A2 SYT2 TLCD4 TMEM14B TMEM35A TMEM45B TMPRSS2 TSNARE1 VAPA VSIR	50 interacting genes: ADGRE2 AGR3 ANKRD46 APP ARLN C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MS4A13 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC33A2 SLC35B4 SLC35E4 SLC38A7 SLC61A1 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A
Entrez ID		161145	93380
HPRD ID		08157	06626
Ensembl ID		ENSG00000198133	ENSG00000169446
Uniprot IDs		Q8NBD8	Q8N4V1
PDB IDs			6WW7 6Z3W 7ADO 7ADP 8EOI 8J0N 8J0O 8S9S 9C7V
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Membrane SNAP Receptor Activity SNARE Complex Membrane Docking Vesicle Docking SNARE Binding Organelle Localization By Membrane Tethering Membrane Fusion Vesicle Fusion Organelle Membrane Fusion Endoplasmic Reticulum Organelle Fusion Protein Binding Endoplasmic Reticulum Membrane Endomembrane System Membrane Organization Intracellular Transport Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Spontaneous Synaptic Transmission Intracellular Protein Transport Other Organism Cell Membrane Membrane Attack Complex Chloride Channel Inhibitor Activity Establishment Of Protein Localization Vesicle Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Vesicle Priming Peroxisome Fission Complement Activation, GZMK Pathway Synaptic Vesicle Docking Astrocyte Projection Transmembrane Transporter Complex Recycling Endosome Mitochondrial Fission Macrophage Activation Positive Regulation Of Synaptic Transmission Complement Activation, Alternative Pathway Protein Transport Cellular Localization Establishment Of Localization In Cell
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