CCDC34 and COQ8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC34	COQ8A
Description		coiled-coil domain containing 34	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Cell Projection Sperm Midpiece	Mitochondrion Membrane Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Enzyme Activator Activity Kinase Activity Transferase Activity ADP Binding
	Biological Process	Spermatogenesis	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways			Ubiquinol biosynthesis
Drugs			Fostamatinib
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3) Coenzyme Q10 deficiency
GWAS		Body mass index ( 29273807) Bone mineral density (paediatric, skull) ( 24945404) Dental caries (decayed, missing and filled teeth) ( 31533690) Heel bone mineral density ( 30598549) Waist circumference ( 28552196)
Interacting Genes		2 interacting genes: COQ8A TMEM86B	27 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 LDAF1 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM239 TPD52L2 UBC
Entrez ID		91057	56997
HPRD ID		14868	07375
Ensembl ID		ENSG00000109881	ENSG00000163050
Uniprot IDs		Q96HJ3	Q8NI60
PDB IDs			4PED 5I35 7UDP 7UDQ
Enriched GO Terms of Interacting Partners?		D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Metabolic Process Quinone Metabolic Process Ubiquinone Biosynthetic Process Ether Lipid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Ketone Biosynthetic Process ADP Binding Phosphate-containing Compound Metabolic Process Phosphatidylcholine Metabolic Process Enzyme Activator Activity Ketone Metabolic Process
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