DHX57 and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DHX57	KRTAP10-6
Description		DExH-box helicase 57	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding RNA Polymerase Binding	Protein Binding
	Biological Process	Positive Regulation Of Translation
Pathways			Keratinization
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		25 interacting genes: CARD10 CBX2 CEP44 EIF4ENIF1 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP9-4 NAA10 PCGF5 PLAGL2 RBMY1A1 RSPO4 ZNF473 ZNF587 ZNF837	87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		90957	386674
HPRD ID		09919	11192
Ensembl ID		ENSG00000163214	ENSG00000188155
Uniprot IDs		Q6P158	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament	Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process
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