EXTL1 and CLDN9

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		EXTL1	CLDN9
Name		exostosin like glycosyltransferase 1	claudin 9
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Plasma Membrane Bicellular Tight Junction Membrane Cell Junction Anchoring Junction
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Glycosyltransferase Activity Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Skeletal System Development Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Symbiont Entry Into Host Cell Bicellular Tight Junction Assembly Tight Junction Organization
Pathways		XBP1(S) activates chaperone genes	Tight junction interactions
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		6 interacting genes: CLDN9 ERGIC3 FNDC9 SDR16C5 TMEM14B TMEM237	17 interacting genes: ADIPOQ AOC3 ARLN BNIP3 CYB561 EMP1 ERMP1 EXTL1 GRM2 IGFBP5 LPAR3 MAL MALL PLPP6 RPRM STX8 VSTM1
Entrez ID		2134	9080
HPRD ID		03441	13071
Ensembl ID		ENSG00000158008	ENSG00000213937
Uniprot IDs		Q92935	O95484
PDB IDs		Not available	6OV2 6OV3
GO Terms Enriched among Interactors		None	Endoplasmic Reticulum Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Chemical Homeostasis Brown Fat Cell Differentiation Mitochondrion Autophagosome Adaptor Activity Negative Regulation Of Synaptic Transmission Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Homeostatic Process