ZNF622 and BEND7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF622	BEND7
Description		zinc finger protein 622	BEN domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Preribosome, Large Subunit Precursor	Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Preribosome Binding	DNA Binding Protein Binding
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Kinase Activity Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diastolic blood pressure ( 30224653) Free thyroxine concentration ( 30367059) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900) Schizophrenia x sex interaction ( 34099189) Skin pigmentation ( 28300201) Smoking status (ever vs never smokers) ( 30643258) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: APP BEND7 CDC42 HMGB2 MACROH2A1 MELK MYBL2 OGT PRKN	75 interacting genes: ANP32B BANF2 BYSL C14orf119 CDC37 CDCA7L CEP44 CHD2 CIB3 CSNK2A1 DDX6 DVL2 DVL3 EAF1 EAF2 EIF1AD EMD FAM124A FAM133A GADD45G GEMIN2 GTPBP3 GYS1 HMBOX1 HSF2BP KANK2 L3MBTL2 LMO3 LNX1 LYAR MAGOHB MBD2 MFAP1 MLX MORF4L1 MORF4L2 MYO15B NAP1L3 NEK6 NIF3L1 NKAPD1 NOL12 NUTF2 OGT OSGIN1 PBLD PIM1 PLEKHF2 POLR3GL PPIG PPP1R37 PRMT3 PRPF40A PSMB1 PSMF1 RAB29 RBM10 RIPPLY1 RPL22 SCNM1 SDCBP SDCBP2 SMARCA2 SPANXN2 THAP1 TLK1 TNPO2 TRIM26 U2AF2 UBL5 USP20 VCX2 WHRN ZCCHC10 ZNF622
Entrez ID		90441	222389
HPRD ID		12278	12570
Ensembl ID		ENSG00000173545	ENSG00000165626
Uniprot IDs		Q969S3	A0AAK2PQJ4 Q8N7W2
PDB IDs		6LQM 6LSR 9GMO
Enriched GO Terms of Interacting Partners?		Regulation Of Purine Nucleotide Metabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Spontaneous Synaptic Transmission Regulation Of ATP Metabolic Process Cellular Response To Manganese Ion RAGE Receptor Binding Regulation Of Small Molecule Metabolic Process Protein-containing Complex Response To Manganese Ion Cellular Component Assembly Cellular Response To Catecholamine Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Neurotransmitter Uptake Response To Catecholamine Negative Regulation Of Transcription By RNA Polymerase II Hemopoiesis Amyloid Fibril Formation Regulation Of Response To Oxidative Stress Positive Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process Negative Regulation Of Gene Expression Chemoattractant Activity Regulation Of Necroptotic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Metabolic Process Negative Regulation Of Protein Localization Condensed Chromosome Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Gene Expression Postsynapse Protein-containing Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II Neuron Projection Organization Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Chemotaxis Positive Regulation Of Developmental Process Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Gene Expression, Epigenetic Protein-containing Complex Organization Regulation Of Glycolytic Process Negative Regulation Of RNA Metabolic Process Mitophagy Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Amylin Binding Regulation Of Transcription By RNA Polymerase II	Nucleoplasm Nucleus Protein Binding RNA Splicing, Via Transesterification Reactions Nuclear Speck MRNA Splicing, Via Spliceosome RNA Splicing RNA Metabolic Process Positive Regulation Of JNK Cascade Sin3-type Complex RNA Processing Nucleic Acid Metabolic Process Non-canonical Inflammasome Complex Assembly Super Elongation Complex Identical Protein Binding Positive Regulation Of Neuron Projection Arborization Frizzled Binding Regulation Of JNK Cascade Transcription Elongation Factor Activity MRNA Processing
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