BEND7 and POLR3GL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEND7	POLR3GL
Description		BEN domain containing 7	RNA polymerase III subunit GL
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process		Transcription By RNA Polymerase III
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diastolic blood pressure ( 30224653) Free thyroxine concentration ( 30367059) Hematocrit ( 32888494) Hemoglobin ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900) Schizophrenia x sex interaction ( 34099189) Skin pigmentation ( 28300201) Smoking status (ever vs never smokers) ( 30643258) White blood cell count ( 32888494)
Interacting Genes		75 interacting genes: ANP32B BANF2 BYSL C14orf119 CDC37 CDCA7L CEP44 CHD2 CIB3 CSNK2A1 DDX6 DVL2 DVL3 EAF1 EAF2 EIF1AD EMD FAM124A FAM133A GADD45G GEMIN2 GTPBP3 GYS1 HMBOX1 HSF2BP KANK2 L3MBTL2 LMO3 LNX1 LYAR MAGOHB MBD2 MFAP1 MLX MORF4L1 MORF4L2 MYO15B NAP1L3 NEK6 NIF3L1 NKAPD1 NOL12 NUTF2 OGT OSGIN1 PBLD PIM1 PLEKHF2 POLR3GL PPIG PPP1R37 PRMT3 PRPF40A PSMB1 PSMF1 RAB29 RBM10 RIPPLY1 RPL22 SCNM1 SDCBP SDCBP2 SMARCA2 SPANXN2 THAP1 TLK1 TNPO2 TRIM26 U2AF2 UBL5 USP20 VCX2 WHRN ZCCHC10 ZNF622	10 interacting genes: BEND7 CCND3 LMO1 M1AP MEOX1 MEOX2 PAX6 RBPMS TFCP2 YAF2
Entrez ID		222389	84265
HPRD ID		12570	14546
Ensembl ID		ENSG00000165626	ENSG00000121851
Uniprot IDs		A0AAK2PQJ4 Q8N7W2	A6NGX6 Q9BT43
PDB IDs			5AFQ
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Protein Binding RNA Splicing, Via Transesterification Reactions Nuclear Speck MRNA Splicing, Via Spliceosome RNA Splicing RNA Metabolic Process Positive Regulation Of JNK Cascade Sin3-type Complex RNA Processing Nucleic Acid Metabolic Process Non-canonical Inflammasome Complex Assembly Super Elongation Complex Identical Protein Binding Positive Regulation Of Neuron Projection Arborization Frizzled Binding Regulation Of JNK Cascade Transcription Elongation Factor Activity MRNA Processing	Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Somite Specification Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Segment Specification HMG Box Domain Binding Somite Development Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Metabolic Process Transcription Coactivator Activity Embryonic Pattern Specification DNA Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Male Meiosis Chromosome Separation Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cyclin D3-CDK6 Complex Regulation Of Transcription By RNA Polymerase II Cyclin D3-CDK4 Complex Pattern Specification Process Regulation Of T Cell Homeostatic Proliferation Sclerotome Development RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Habenula Development Pallium Development Male Meiosis Chromosome Segregation Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification MRNA CDS Binding Meiotic Chromosome Separation Forebrain Dorsal/ventral Pattern Formation Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization
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