MED30 and MED22

Number of citations of the paper that reports this interaction (PMID 12584197)
12

Data Source:
HPRD (in vivo)

		MED30	MED22
Gene Name		mediator complex subunit 30	mediator complex subunit 22
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex	Cytoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Kawasaki disease ( 22446961)
Protein-Protein Interactions		13 interactors: APP DOCK8 KRTAP10-9 MED17 MED22 MED27 MED28 MED4 MED8 MED9 MTA2 PCBD2 SS18L1	9 interactors: GOLM1 MED11 MED17 MED27 MED30 MED7 MED8 MED9 THOC7
Entrez ID		90390	6837
HPRD ID		11631	01713
Ensembl ID		ENSG00000164758	ENSG00000148297
Uniprot IDs		Q96HR3	Q15528
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process DNA-templated Transcription, Initiation Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Stem Cell Maintenance Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Stem Cell Development Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Stem Cell Differentiation Positive Regulation Of Metabolic Process Memory T Cell Proliferation Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Cell Development Collateral Sprouting In Absence Of Injury Cell Recognition Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Negative Regulation Of Smooth Muscle Cell Differentiation	Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Stem Cell Maintenance Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Stem Cell Development Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cell Differentiation Androgen Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Viral MRNA Export From Host Cell Nucleus Cell Development Cellular Metabolic Process Intracellular Transport Of Virus MRNA Export From Nucleus RNA Export From Nucleus Cell Differentiation
Tagcloud ?		abundant attenuated branching communicates communications double ductal e2f1 employing ers functionally gland glands haploinsufficient heterozygous knockout lactation luciferase luminal mammary med1 med24 mediator normally profound pubertal puberty retardation submodule
Tagcloud (Difference) ?		abundant attenuated branching communicates communications double ductal e2f1 employing ers functionally gland glands haploinsufficient heterozygous knockout lactation luciferase luminal mammary med1 med24 mediator normally profound pubertal puberty retardation submodule
Tagcloud (Intersection) ?