UNC5A and NTN1

Number of citations of the paper that reports this interaction (PMID 12810718)
23

Data Source:
BioGRID (pull down)

		UNC5A	NTN1
Gene Name		unc-5 homolog A (C. elegans)	netrin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Cytoplasm
	Molecular Function		Protein Binding
	Biological Process	Axon Guidance Anterior/posterior Axon Guidance Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway	Neuron Migration Apoptotic Process Axon Guidance Positive Regulation Of Cell Proliferation Single Organismal Cell-cell Adhesion Regulation Of Cell Migration Negative Regulation Of Axon Extension Anterior/posterior Axon Guidance Establishment Of Nucleus Localization Inner Ear Morphogenesis Positive Regulation Of Axon Extension Mammary Gland Duct Morphogenesis
Pathways		Axon guidance Programmed Cell Death Netrin mediated repulsion signals Netrin-1 signaling Role of DCC in regulating apoptosis Extrinsic Pathway	DSCAM interactions Axon guidance Role of second messengers in netrin-1 signaling DCC mediated attractive signaling Netrin mediated repulsion signals Netrin-1 signaling
Drugs
Diseases
GWAS			Breast cancer (prognosis) ( 23319801)
Protein-Protein Interactions		3 interactors: DAPK1 MAGED1 NTN1	5 interactors: ADORA2B DCC NEO1 UNC5A UNC5C
Entrez ID		90249	9423
HPRD ID		12131	03368
Ensembl ID		ENSG00000113763	ENSG00000065320
Uniprot IDs		Q6ZN44	O95631
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Anterior/posterior Axon Guidance Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Negative Regulation Of Axon Extension Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Establishment Of Nucleus Localization	Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Response To External Stimulus Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cell Development Positive Regulation Of Cell Death Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Nervous System Development Anatomical Structure Morphogenesis Spinal Cord Ventral Commissure Morphogenesis Apoptotic Process Programmed Cell Death Dorsal/ventral Axon Guidance Cell Death Death Negative Regulation Of Collateral Sprouting Positive Regulation Of Chronic Inflammatory Response Relaxation Of Vascular Smooth Muscle Cell Differentiation Apoptotic Signaling Pathway Relaxation Of Smooth Muscle Regulation Of Apoptotic Process Positive Regulation Of Guanylate Cyclase Activity Regulation Of Cell Death Positive Regulation Of Mast Cell Degranulation Regulation Of Chronic Inflammatory Response Adenosine Receptor Signaling Pathway Positive Regulation Of Mast Cell Activation Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Dendrite Development Positive Regulation Of MAPK Cascade
Tagcloud ?		allows attraction axons charged chemotropic cone contradictory cue dcc deleted depending eliciting generic guidance migrating modularity netrin patches puzzle repertoire replace repulsion simultaneously staple sulfate switch trigger turning ways	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?		allows attraction axons charged chemotropic cone contradictory cue dcc deleted depending eliciting generic guidance migrating modularity netrin patches puzzle repertoire replace repulsion simultaneously staple sulfate switch trigger turning ways	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?