NTN1 and UNC5C

Number of citations of the paper that reports this interaction (PMID 12810718)
23

Data Source:
HPRD (in vitro)

		NTN1	UNC5C
Gene Name		netrin 1	unc-5 homolog C (C. elegans)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Netrin Receptor Activity
	Biological Process	Neuron Migration Apoptotic Process Axon Guidance Positive Regulation Of Cell Proliferation Single Organismal Cell-cell Adhesion Regulation Of Cell Migration Negative Regulation Of Axon Extension Anterior/posterior Axon Guidance Establishment Of Nucleus Localization Inner Ear Morphogenesis Positive Regulation Of Axon Extension Mammary Gland Duct Morphogenesis	Apoptotic Process Axon Guidance Brain Development Regulation Of Cell Migration Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Positive Regulation Of Apoptotic Process
Pathways		DSCAM interactions Axon guidance Role of second messengers in netrin-1 signaling DCC mediated attractive signaling Netrin mediated repulsion signals Netrin-1 signaling	Axon guidance Netrin mediated repulsion signals Netrin-1 signaling
Drugs
Diseases
GWAS		Breast cancer (prognosis) ( 23319801)	Obesity-related traits ( 23251661) P-tau181p ( 20932310)
Protein-Protein Interactions		5 interactors: ADORA2B DCC NEO1 UNC5A UNC5C	2 interactors: DAPK1 NTN1
Entrez ID		9423	8633
HPRD ID		03368	04678
Ensembl ID		ENSG00000065320	ENSG00000182168
Uniprot IDs		O95631	A8K385 O95185
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Response To External Stimulus Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cell Development Positive Regulation Of Cell Death Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Nervous System Development Anatomical Structure Morphogenesis Spinal Cord Ventral Commissure Morphogenesis Apoptotic Process Programmed Cell Death Dorsal/ventral Axon Guidance Cell Death Death Negative Regulation Of Collateral Sprouting Positive Regulation Of Chronic Inflammatory Response Relaxation Of Vascular Smooth Muscle Cell Differentiation Apoptotic Signaling Pathway Relaxation Of Smooth Muscle Regulation Of Apoptotic Process Positive Regulation Of Guanylate Cyclase Activity Regulation Of Cell Death Positive Regulation Of Mast Cell Degranulation Regulation Of Chronic Inflammatory Response Adenosine Receptor Signaling Pathway Positive Regulation Of Mast Cell Activation Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Dendrite Development Positive Regulation Of MAPK Cascade
Tagcloud ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 polyp signatures slc9a2 vwf	ancient archaea autoproteolysis autoproteolytic card8 deteriorated extend fam171 fiind gpcr gpcrs gps hfs hlt lrr nacht nlrp1 nucleoporin98 nup98 occluden origination polycystic precedes pyd searches subdomain upa zonula zu5
Tagcloud (Difference) ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 polyp signatures slc9a2 vwf	ancient archaea autoproteolysis autoproteolytic card8 deteriorated extend fam171 fiind gpcr gpcrs gps hfs hlt lrr nacht nlrp1 nucleoporin98 nup98 occluden origination polycystic precedes pyd searches subdomain upa zonula zu5
Tagcloud (Intersection) ?