UNC5A

Description		unc-5 netrin receptor A
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection Membrane Neuronal Cell Body Membrane Cell Projection Neuron Projection Membrane Raft
	Molecular Function	Netrin Receptor Activity
	Biological Process	Apoptotic Process Signal Transduction Neuron Projection Development Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway
Pathways		Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: DAPK1 MAGED1 NTN1
Entrez ID		90249
HPRD ID		12131
Ensembl ID		ENSG00000113763
Uniprot IDs		H0Y8R2 Q6ZN44
PDB IDs		4V2A
Enriched GO Terms of Interacting Partners?		DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of NMDA Receptor Activity Actin Cytoskeleton Cdc42 Protein Signal Transduction Cellular Response To Hydroperoxide Defense Response To Tumor Cell Chemorepulsion Of Axon Substrate-dependent Cell Migration, Cell Extension Anterior/posterior Axon Guidance Mammary Gland Duct Morphogenesis Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Calcium/calmodulin-dependent Protein Kinase Activity Response To Hydroperoxide Glutamatergic Synapse Regulation Of Neurotransmitter Receptor Activity Syntaxin-1 Binding Motor Neuron Migration Regulation Of Glial Cell Migration Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Glial Cell Proliferation
Tagcloud ?