CFAP91 and PRKAR2B

Number of citations of the paper that reports this interaction (PubMedID 12223483)
0

Data Source:
BioGRID (pull down)

		CFAP91	PRKAR2B
Description		cilia and flagella associated protein 91	protein kinase cAMP-dependent type II regulatory subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Stalk Cytoplasm Mitochondrion Cytoskeleton Axoneme Motile Cilium Cell Projection	Cytoplasm Centrosome Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Membrane Dendrite Neuronal Cell Body Dendritic Spine Dendritic Shaft Perinuclear Region Of Cytoplasm Extracellular Exosome Ciliary Base Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Nucleotide Binding CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity Protein Kinase Binding Protein Domain Specific Binding CAMP Binding Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding
	Biological Process	Cilium Movement Spermatogenesis Cell Differentiation Axonemal Central Apparatus Assembly	Fatty Acid Metabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Learning Intracellular Signal Transduction Modulation Of Chemical Synaptic Transmission Response To Antipsychotic Drug Negative Regulation Of CAMP/PKA Signal Transduction
Pathways			PKA activation PKA activation in glucagon signalling DARPP-32 events Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs			Cyclic adenosine monophosphate
Diseases
GWAS			Adverse response to lamotrigine and phenytoin ( 22379998) Bladder cancer (smoking interaction) ( 24662972) Blood urea nitrogen levels ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Manganese levels ( 26025379) Response to antipsychotic treatment ( 20195266) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: AKAP1 DPY30 DSCAM MYCBP PRKAR2B	17 interacting genes: AKAP1 AKAP10 AKAP11 AKAP14 AKAP19 AKAP4 AKAP5 AKAP9 CFAP91 ECM1 GNAI3 KIF5B LASP1 NBEA OGT PAK1IP1 TAF12
Entrez ID		89876	5577
HPRD ID		10782	01486
Ensembl ID		ENSG00000183833	ENSG00000005249
Uniprot IDs		Q7Z4T9	B3KY43 P31323
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Mediator Activity Neuronal Cell Body Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Response To Antipsychotic Drug	Protein Kinase A Regulatory Subunit Binding Protein Kinase A Binding Negative Regulation Of Adenylate Cyclase Activity CAMP-dependent Protein Kinase Complex
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