ATG16L2 and RAB33A

Number of citations of the paper that reports this interaction (PubMedID 22082872)
41

Data Source:
BioGRID (two hybrid)

		ATG16L2	RAB33A
Description		autophagy related 16 like 2	RAB33A, member RAS oncogene family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Autophagosome Cytosol Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Golgi Membrane Endosome Golgi Apparatus Plasma Membrane Membrane
	Molecular Function		Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Autophagosome Assembly Autophagy Protein Transport Macroautophagy Negative Stranded Viral RNA Replication	Autophagosome Assembly Antigen Processing And Presentation Rab Protein Signal Transduction
Pathways		Macroautophagy	TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Crohn's disease ( 23266558 23850713) Non-albumin protein levels ( 29403010) Systemic lupus erythematosus ( 26663301)	Bipolar disorder ( 31043756) Height ( 31562340)
Interacting Genes		4 interacting genes: ATG5 RAB33A RAB33B TK1	15 interacting genes: ARL6IP1 ATG16L1 ATG16L2 CCDC136 KRT31 KRT34 LNX1 LRP2BP PSMF1 RABAC1 RTN3 RTN4 RUFY2 RUFY3 SIAH1
Entrez ID		89849	9363
HPRD ID		10959	02272
Ensembl ID		ENSG00000168010	ENSG00000134594
Uniprot IDs		Q8NAA4	Q14088
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagosome Organization Autophagosome Assembly Rab Protein Signal Transduction Vacuole Organization Phagophore Assembly Site Membrane Cellular Component Assembly Thymidine Kinase Activity Organelle Assembly Antigen Processing And Presentation Otolith Development Positive Regulation Of Viral Translation Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER DNA Synthesis Involved In Mitotic DNA Replication Negative Regulation Of Autophagic Cell Death Phagophore Atg8-family Ligase Activity Negative Stranded Viral RNA Replication Response To Fluoride Cellular Response To Nitrosative Stress Thymidine Biosynthetic Process Positive Regulation Of Mucus Secretion Thymidine Metabolic Process Small GTPase-mediated Signal Transduction Positive Regulation Of Stress Granule Assembly Chaperone-mediated Autophagy Response To Iron(II) Ion Viral RNA Genome Replication Atg12-Atg5-Atg16 Complex Autophagy Regulation Of Mucus Secretion Response To Nitrosative Stress GTPase Activity Deoxyribonucleoside Monophosphate Biosynthetic Process Ventricular Cardiac Muscle Cell Development Cellular Response To Nitrogen Starvation GTP Binding Regulation Of Stress Granule Assembly Pyrimidine Nucleoside Metabolic Process Cardiac Muscle Cell Apoptotic Process Negative Thymic T Cell Selection Negative T Cell Selection Transferase Complex Aggrephagy Striated Muscle Cell Apoptotic Process Regulation Of Autophagosome Maturation Mucus Secretion Negative Regulation Of Transport Nucleotide Binding Negative Regulation Of Defense Response To Virus	Endoplasmic Reticulum Tubular Network Formation Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Negative Stranded Viral RNA Replication Atg12-Atg5-Atg16 Complex Viral RNA Genome Replication Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Phagophore Assembly Site Membrane Viral Genome Replication Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Organelle Organization GTPase Binding Supramolecular Fiber Organization Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Amyloid-beta Formation Negative Regulation Of Axonogenesis Vacuole-isolation Membrane Contact Site Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Structural Constituent Of Skin Epidermis Nervous System Development Positive Regulation Of Retrograde Axon Cargo Transport C-terminal Protein Lipidation Intermediate Filament Organization Cell Differentiation Regulation Of Amide Metabolic Process Regulation Of Axon Extension Autophagosome Regulation Of Developmental Growth Positive Regulation Of Protein Localization To Endoplasmic Reticulum Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Negative Regulation Of Developmental Growth Positive Regulation Of L-glutamate Import Across Plasma Membrane Negative Regulation Of Dendrite Extension Cell Migration Involved In Vasculogenesis Autophagosome Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Branching Morphogenesis Of A Nerve Intracellular Sphingolipid Homeostasis Central Nervous System Vasculogenesis Endoplasmic Reticulum Tubular Network Membrane Regulation Of Cell Growth Negative Regulation Of Neuron Projection Development
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