EIF2B3 and GOLM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		EIF2B3	GOLM1
Description		eukaryotic translation initiation factor 2B subunit gamma	golgi membrane protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding	Protein Binding
	Biological Process	Cytoplasmic Translational Initiation Translation Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone T Cell Receptor Signaling Pathway	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways		Recycling of eIF2:GDP	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Platelet distribution width ( 32888494)	Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2	76 interacting genes: ABI3 AIG1 ANKRD46 ASPH B3GNT4 BCL2L1 C1orf174 C1QL4 CDIPT CIAO1 CLDN4 CLDND2 CLK1 CNPY3 DCK DCTN2 DESI1 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 FUT9 GALNT15 GAST GEMIN7 GET3 GLB1 GRIK5 GUCA2A HGFAC HMGB1 HSD17B13 IGFBP5 INSIG2 JAGN1 KCNE3 LAT LSM12 MED22 MIP NDUFV2 NEU1 NINJ1 NIPSNAP3A NRSN2 PGRMC1 RACK1 RIPPLY2 RPA2 RPL13A SFTPC SLC13A5 SLC30A3 SLC40A1 SLC5A4 SLCO3A1 ST6GAL2 STRIT1 SYT1 TF THSD7A TMEM109 TMEM140 TMEM147 TMEM176A TMEM86B TMEM98 TMPO TMUB1 TMUB2 TSG101 VSTM1 ZFAND3
Entrez ID		8891	51280
HPRD ID		09379	08428
Ensembl ID		ENSG00000070785	ENSG00000135052
Uniprot IDs		Q9HA31 Q9NR50	B3KNK9 Q8NBJ4
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z 7D43 7D44 7D45 7D46 7F64 7F66 7F67 7KMF 7L70 7L7G 7RLO 7TRJ 7VLK 8TQO 8TQZ	8YBC
Enriched GO Terms of Interacting Partners?		Eukaryotic Translation Initiation Factor 2 Complex Endoplasmic Reticulum Unfolded Protein Response Translation Initiation Ternary Complex Translation Initiation Factor Activity Histone H3K36me2/H3K36me3 Demethylase Activity Translational Initiation Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Male Germ Cell Proliferation	Membrane
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