EIF2B3 and NDUFB8

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF2B3	NDUFB8
Description		eukaryotic translation initiation factor 2B subunit gamma	NADH:ubiquinone oxidoreductase subunit B8
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Respiratory Chain Complex I
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Cytoplasmic Translational Initiation Translation Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone T Cell Receptor Signaling Pathway	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Recycling of eIF2:GDP	Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Platelet distribution width ( 32888494)	Brain morphology (MOSTest) ( 32665545) Palmitoleic acid (16:1n-7) levels ( 23362303)
Interacting Genes		5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2	6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70
Entrez ID		8891	4714
HPRD ID		09379	11886
Ensembl ID		ENSG00000070785	ENSG00000166136
Uniprot IDs		Q9HA31 Q9NR50	O95169
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z 7D43 7D44 7D45 7D46 7F64 7F66 7F67 7KMF 7L70 7L7G 7RLO 7TRJ 7VLK 8TQO 8TQZ	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Eukaryotic Translation Initiation Factor 2 Complex Endoplasmic Reticulum Unfolded Protein Response Translation Initiation Ternary Complex Translation Initiation Factor Activity Histone H3K36me2/H3K36me3 Demethylase Activity Translational Initiation Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Male Germ Cell Proliferation
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