STC2 and PLA2G5

		STC2	PLA2G5
Description		stanniocalcin 2	phospholipase A2 group V
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Extracellular Region Endosome Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Early Phagosome Phagolysosome Phagocytic Vesicle Recycling Endosome
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	Phospholipase A2 Activity Calcium Ion Binding Phospholipid Binding Hydrolase Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Lipid Metabolic Process Fatty Acid Metabolic Process Phospholipid Metabolic Process Phagocytosis Phospholipid Catabolic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Macrophage Derived Foam Cell Differentiation Lipid Catabolic Process Leukotriene Biosynthetic Process Low-density Lipoprotein Particle Remodeling Phosphatidylcholine Catabolic Process Negative Regulation Of T Cell Proliferation Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Arachidonate Secretion Positive Regulation Of Phagocytosis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Phagosome-lysosome Fusion Positive Regulation Of Opsonization Positive Regulation Of Antifungal Innate Immune Response Positive Regulation Of Phagosome Maturation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Interacting Genes		11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN	1 interacting genes: PLA2G4A
Entrez ID		8614	5322
HPRD ID		04717	03117
Ensembl ID		ENSG00000113739	ENSG00000127472
Uniprot IDs		O76061 Q6FHC9	P39877
PDB IDs		7Y5Q 8A7D 8A7E 8HGH
Enriched GO Terms of Interacting Partners?			UDP-glucose 4-epimerase Activity UDP-N-acetylglucosamine 4-epimerase Activity Organophosphate Catabolic Process Phosphatidylglycerol Catabolic Process Galactose Metabolic Process Galactose Catabolic Process Carbohydrate Metabolic Process Galactose Catabolic Process Via UDP-galactose, Leloir Pathway Platelet Activating Factor Metabolic Process Cellular Response To Antibiotic Calcium-independent Phospholipase A2 Activity Calcium-dependent Phospholipase A2 Activity Positive Regulation Of Platelet Activation Ether Lipid Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Phosphatidylcholine Catabolic Process Ceramide 1-phosphate Binding Glycerol Metabolic Process Positive Regulation Of Prostaglandin Secretion Monoacylglycerol Biosynthetic Process Platelet Activating Factor Biosynthetic Process Negative Regulation Of Multicellular Organism Growth Regulation Of Store-operated Calcium Entry Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Phosphatidylinositol-5-phosphate Binding O-acyltransferase Activity Positive Regulation Of Fatty Acid Transport Positive Regulation Of Icosanoid Secretion Arachidonate Secretion Ether Lipid Metabolic Process Glycerophospholipid Catabolic Process Phosphatidylcholine Lysophospholipase Activity Positive Regulation Of T-helper 1 Type Immune Response Leukotriene Biosynthetic Process Decidualization Regulation Of Hormone Biosynthetic Process Phospholipase Activity Protein Homodimerization Activity Leukotriene Metabolic Process Phospholipase A2 Activity Positive Regulation Of Macrophage Activation Phosphatidylinositol-4-phosphate Binding Phosphatidylglycerol Metabolic Process Response To Vitamin D Regulation Of Fatty Acid Transport Prostaglandin Metabolic Process Prostanoid Metabolic Process Response To Antibiotic Carboxylic Ester Hydrolase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?