RUVBL1 and NUFIP1

Number of citations of the paper that reports this interaction (PMID 17636026)
22

Data Source:
BioGRID (pull down)

		RUVBL1	NUFIP1
Gene Name		RuvB-like AAA ATPase 1	nuclear fragile X mental retardation protein interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Organizing Center Membrane Nuclear Matrix Ino80 Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome MLL1 Complex	Nucleus Nucleoplasm Perichromatin Fibrils Nucleolus Transcription Elongation Factor Complex Nuclear Matrix Cytosolic Ribosome Protein Complex Presynaptic Active Zone Pre-snoRNP Complex
	Molecular Function	DNA Helicase Activity Protein Binding ATP Binding ATPase Activity	DNA Binding RNA Binding Protein Binding SnoRNA Binding Protein Binding, Bridging Identical Protein Binding Metal Ion Binding
	Biological Process	DNA Repair DNA Recombination Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Nuclear Division Spermatogenesis DNA Duplex Unwinding CENP-A Containing Nucleosome Assembly Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Cell Division	Box C/D SnoRNP Assembly RNA Processing Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Chromosome Maintenance Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling formation of the beta-catenin:TCF transactivating complex Deposition of new CENPA-containing nucleosomes at the centromere Telomere Extension By Telomerase Extension of Telomeres Signaling by Wnt HATs acetylate histones Chromatin modifying enzymes Telomere Maintenance Nucleosome assembly TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer
Drugs
Diseases
GWAS			Oleic acid (18:1n-9) plasma levels ( 23362303)
Protein-Protein Interactions		20 interactors: ACTL6A CTNNB1 DKC1 FBL HDAC1 KIAA1377 LZTR1 MRGBP MYC NEDD4 NUFIP1 OFD1 PIH1D1 PLG RUVBL2 STOM TAF9 TBP TERT TK1	7 interactors: BRCA1 CCNT1 FMR1 KLF6 RUVBL1 RUVBL2 TAF9
Entrez ID		8607	26747
HPRD ID		09143	05073
Ensembl ID		ENSG00000175792	ENSG00000083635
Uniprot IDs		Q9Y265	Q9UHK0
PDB IDs		2C9O 2XSZ
Enriched GO Terms of Interacting Partners?		Chromatin Modification Chromosome Organization Chromatin Organization Organelle Organization RNA Metabolic Process Box C/D SnoRNP Assembly Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Histone Modification Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Gene Expression Cellular Response To UV Cellular Nitrogen Compound Metabolic Process Fungiform Papilla Formation Gene Expression Negative Regulation Of Signaling Telomere Maintenance Via Telomerase DNA-templated Transcription, Initiation Fungiform Papilla Morphogenesis Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Fungiform Papilla Development RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Light Stimulus Developmental Process Nitrogen Compound Metabolic Process Histone H2A Acetylation Hair Follicle Placode Formation Cellular Component Assembly Tongue Morphogenesis DNA Biosynthetic Process Histone Acetylation Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA-dependent DNA Replication Protein Acetylation Response To UV Regulation Of Transcription, DNA-templated	Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process DNA Recombination Peptidyl-lysine Modification Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone Acetylation Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone H4 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Histone Modification Transcription, DNA-templated Positive Regulation Of Histone Modification RNA Biosynthetic Process DNA Duplex Unwinding DNA Geometric Change Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Organic Substance DNA-templated Transcription, Elongation Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process DNA Repair Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		anaemia aplastic assemble atpases conditional confers core crosslinker crosslinks depletion encode fa fanconi haematopoietic hallmark instability interstrand lethal monoubiquitin multisubunit pool profound purify repairs senses stringent surprisingly vertebrate
Tagcloud (Difference) ?		anaemia aplastic assemble atpases conditional confers core crosslinker crosslinks depletion encode fa fanconi haematopoietic hallmark instability interstrand lethal monoubiquitin multisubunit pool profound purify repairs senses stringent surprisingly vertebrate
Tagcloud (Intersection) ?