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API5 and SLAMF7
API5
SLAMF7
Description
apoptosis inhibitor 5
SLAM family member 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Spliceosomal Complex
Cytoplasm
Membrane
Nuclear Speck
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Molecular Function
RNA Binding
Protein Binding
Fibroblast Growth Factor Binding
Identical Protein Binding
Biological Process
Apoptotic Process
Negative Regulation Of Apoptotic Process
Fibroblast Apoptotic Process
Negative Regulation Of Fibroblast Apoptotic Process
Adaptive Immune Response
Immune System Process
Immune Response
Cell Adhesion
Natural Killer Cell Activation
T Cell Activation
Natural Killer Cell Mediated Cytotoxicity
Innate Immune Response
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Elotuzumab
Diseases
GWAS
Alzheimer's disease (
33074286
)
Cognitive performance (
19734545
)
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Response to bupropion in depression (
27622933
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Blood protein levels (
30072576
)
IgM levels (
28628107
)
Inflammatory bowel disease (
23128233
)
Microalbuminuria (
26631737
)
Multiple sclerosis (
24076602
)
Interacting Genes
3 interacting genes:
BICDL2
FGF2
OGT
4 interacting genes:
CLK3
MAK
SH2D1A
TRIB2
Entrez ID
8539
57823
HPRD ID
16500
09432
Ensembl ID
ENSG00000166181
ENSG00000026751
Uniprot IDs
B4DDR3
Q9BZZ5
B4DVL7
B4DW98
Q9NQ25
PDB IDs
3U0R
3V6A
6L4O
Enriched GO Terms of Interacting Partners
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Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation
Response To Wortmannin
Positive Regulation Of Inner Ear Receptor Cell Differentiation
Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Angiogenesis Involved In Coronary Vascular Morphogenesis
Regulation Of Retinal Cell Programmed Cell Death
Lymphatic Endothelial Cell Migration
Positive Regulation Of Cell Fate Specification
Positive Regulation Of Lens Fiber Cell Differentiation
Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Corticotropin Hormone Secreting Cell Differentiation
Protein N-acetylglucosaminyltransferase Complex
Negative Regulation Of Non-canonical Inflammasome Complex Assembly
Protein O-acetylglucosaminyltransferase Activity
Golgi To Secretory Granule Transport
Chemokine Binding
Negative Regulation Of Cell Migration
Receptor-receptor Interaction
Thyroid-stimulating Hormone-secreting Cell Differentiation
Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Regulation Of Lens Fiber Cell Differentiation
Chondroblast Differentiation
Cerebellar Granule Cell Precursor Proliferation
Negative Regulation Of Cell Motility
Positive Regulation Of Neuroepithelial Cell Differentiation
Positive Regulation Of Blood Vessel Branching
Regulation Of Cerebellar Granule Cell Precursor Proliferation
Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Regulation Of Cellular Response To Growth Factor Stimulus
Cell Proliferation In External Granule Layer
Behavioral Response To Ethanol
Regulation Of Blood Vessel Branching
Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation
Paracrine Signaling
Positive Regulation Of Epithelial Tube Formation
Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Non-canonical Inflammasome Complex Assembly
Regulation Of Transcription By Glucose
Positive Regulation Of Transcription By Glucose
Carbon Catabolite Regulation Of Transcription
Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Negative Regulation Of Locomotion
NSL Complex
Negative Regulation Of Fibroblast Migration
Regulation Of Skeletal Muscle Satellite Cell Proliferation
Hyaluronan Catabolic Process
Positive Regulation Of Cell Fate Commitment
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Endothelial Cell Chemotaxis
Regulation Of Skeletal Muscle Cell Proliferation
Cytoplasm
Negative Regulation Of Uterine Smooth Muscle Contraction
Alpha-1B Adrenergic Receptor Binding
Alpha-2C Adrenergic Receptor Binding
Phospholipase C-activating Adrenergic Receptor Signaling Pathway
Protein Homodimerization Activity
Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway
Protein Phosphorylation
Negative Regulation Of Non-motile Cilium Assembly
Skeletal Muscle Tissue Development
Left Lung Morphogenesis
Superior Vena Cava Morphogenesis
Prolactin Secreting Cell Differentiation
Cell Proliferation Involved In Outflow Tract Morphogenesis
Pulmonary Vein Morphogenesis
Subthalamic Nucleus Development
Regulation Of Actin Filament Depolymerization
Actin Filament Capping
Negative Regulation Of Protein-containing Complex Disassembly
Negative Regulation Of Actin Filament Depolymerization
Negative Regulation Of Actin Filament Polymerization
Pantothenate Kinase Activity
Regulation Of Protein Depolymerization
Actin Filament-based Process
Alpha2-adrenergic Receptor Activity
Phosphorylation
Pulmonary Myocardium Development
Endodermal Digestive Tract Morphogenesis
Deltoid Tuberosity Development
Norepinephrine Binding
Thermoception
Somatotropin Secreting Cell Differentiation
Cell Proliferation Involved In Heart Morphogenesis
Acetyl-CoA Binding
Negative Regulation Of Norepinephrine Secretion
Epinephrine Binding
Negative Regulation Of Epinephrine Secretion
Protein Kinase Activity
Striated Muscle Tissue Development
Embryonic Heart Tube Left/right Pattern Formation
Muscle Structure Development
Extraocular Skeletal Muscle Development
Atrioventricular Valve Development
Regulation Of Actin Filament Polymerization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Protein-containing Complex Disassembly
Negative Regulation Of Protein-containing Complex Assembly
Ubiquitin-protein Transferase Regulator Activity
Pointed-end Actin Filament Capping
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