API5

Description		apoptosis inhibitor 5
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytoplasm Membrane Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Fibroblast Growth Factor Binding
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Fibroblast Apoptotic Process Negative Regulation Of Fibroblast Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 33074286) Cognitive performance ( 19734545) Metabolite levels ( 23823483) Refractive error ( 32231278) Response to bupropion in depression ( 27622933) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Novel Interacting Genes		1 novel interacting genes: SLAMF7
Interacting Genes		3 interacting genes: BICDL2 FGF2 OGT
Entrez ID		8539
HPRD ID		16500
Ensembl ID		ENSG00000166181
Uniprot IDs		B4DDR3 Q9BZZ5
PDB IDs		3U0R 3V6A 6L4O
Enriched GO Terms of Interacting Partners?		Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Angiogenesis Involved In Coronary Vascular Morphogenesis Regulation Of Retinal Cell Programmed Cell Death Lymphatic Endothelial Cell Migration Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Corticotropin Hormone Secreting Cell Differentiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein O-acetylglucosaminyltransferase Activity Golgi To Secretory Granule Transport Chemokine Binding Negative Regulation Of Cell Migration Receptor-receptor Interaction Thyroid-stimulating Hormone-secreting Cell Differentiation Regulation Of Inner Ear Auditory Receptor Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Chondroblast Differentiation Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Cell Motility Positive Regulation Of Neuroepithelial Cell Differentiation Positive Regulation Of Blood Vessel Branching Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Regulation Of Cellular Response To Growth Factor Stimulus Cell Proliferation In External Granule Layer Behavioral Response To Ethanol Regulation Of Blood Vessel Branching Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Paracrine Signaling Positive Regulation Of Epithelial Tube Formation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Regulation Of Transcription By Glucose Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Locomotion NSL Complex Negative Regulation Of Fibroblast Migration Regulation Of Skeletal Muscle Satellite Cell Proliferation Hyaluronan Catabolic Process Positive Regulation Of Cell Fate Commitment Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Skeletal Muscle Cell Proliferation
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