KRTAP9-4 and MAPKBP1

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		KRTAP9-4	MAPKBP1
Name		keratin associated protein 9-4	mitogen-activated protein kinase binding protein 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoskeleton Mitotic Spindle Pole
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	None	Negative Regulation Of Interleukin-8 Production Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade Negative Regulation Of Defense Response To Bacterium Regulation Of Intracellular Signal Transduction
Pathways		Keratinization	None
GWAS		No GWAS studies recorded	A body shape index ( 34021172 ) Appendicular lean mass ( 33097823 ) Diastolic blood pressure ( 27841878 ) Urinary albumin excretion ( 30220432 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 ) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226 )
Interacting Genes		29 interacting genes: ADAMTSL4 CATSPER1 CREB5 DHX57 DOCK2 FBXW5 HOXA1 KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE3C LCE3E LCE4A MAPKBP1 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PRKAB2 REL SMCP SPRY2 YIPF3	65 interacting genes: ADAM12 ADAMTSL4 ALG13 APTX CRYAA CTDSP1 CYSRT1 FOXN1 FXR1 FXR2 GLRX3 HOXA1 KEAP1 KPRP KRT31 KRT34 KRT35 KRT38 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 MAPK10 MAPK8 MAPK9 MDFI MEOX2 METTL15 MYOG NBPF19 NOTCH2NLA PLA2G10 PLSCR3 RBCK1 RGS20 SIAH1 SPRY2 SPRY3 TCF12 TCF4 TEKT5 TEX11 TRIM27 TRIM42 TRIP6 YPEL5 ZNF34
Entrez ID		85280	23005
HPRD ID		13951	17465
Ensembl ID		ENSG00000241595	ENSG00000137802
Uniprot IDs		Q9BYQ2	O60336
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Epidermis Development Keratinization Identical Protein Binding	Intermediate Filament Keratin Filament Structural Molecule Activity Structural Constituent Of Skin Epidermis Cytosol JUN Kinase Activity Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Epidermis Development MAP Kinase Activity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Identical Protein Binding Supramolecular Fiber Organization Fc-epsilon Receptor Signaling Pathway Morphogenesis Of An Epithelium MRNA Destabilization Positive Regulation Of Long-term Neuronal Synaptic Plasticity RNA Destabilization Protein Binding Tissue Morphogenesis Positive Regulation Of MRNA Catabolic Process Regulation Of Circadian Rhythm