CEP19 and FGFR1OP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP19	FGFR1OP
Gene Name		centrosomal protein 19kDa	FGFR1 oncogene partner
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centriole Ciliary Basal Body	Nucleus Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Tyrosine Kinase Activity Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Organelle Organization Positive Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways			Organelle biogenesis and maintenance Signaling by FGFR in disease Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Signaling by FGFR1 mutants Loss of Nlp from mitotic centrosomes Signaling by FGFR mutants Centrosome maturation Signaling by FGFR1 fusion mutants Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS			Graves' disease ( 21841780) Vitiligo ( 20526339)
Protein-Protein Interactions		13 interactors: AK4 CALCOCO1 CCDC102B CREB3L2 FGFR1OP KIAA1958 KXD1 RABL2A RABL2B REL SYNE4 VCP ZBTB14	4 interactors: CEP19 NAGK PPP2R1B VASP
Entrez ID		84984	11116
HPRD ID		17488	10392
Ensembl ID		ENSG00000174007
Uniprot IDs		Q96LK0	B4DH64 O95684
PDB IDs			2D68
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Establishment Of Epithelial Cell Apical/basal Polarity Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Cellular Protein Localization Regulation Of Protein Deubiquitination Cellular Localization Protein Hexamerization ADP Biosynthetic Process Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Transport Ras Protein Signal Transduction Establishment Of Monopolar Cell Polarity Aggresome Assembly Translesion Synthesis Nucleoside Diphosphate Biosynthetic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Golgi Vesicle Transport ADP Metabolic Process	N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process N-acetylneuraminate Metabolic Process
Tagcloud ?			aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Difference) ?			aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Intersection) ?