FGFR1OP and CEP19

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FGFR1OP	CEP19
Gene Name		FGFR1 oncogene partner	centrosomal protein 19kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Perinuclear Region Of Cytoplasm	Spindle Pole Centriole Ciliary Basal Body
	Molecular Function	Protein Tyrosine Kinase Activity Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Organelle Organization Positive Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Organelle biogenesis and maintenance Signaling by FGFR in disease Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Signaling by FGFR1 mutants Loss of Nlp from mitotic centrosomes Signaling by FGFR mutants Centrosome maturation Signaling by FGFR1 fusion mutants Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Graves' disease ( 21841780) Vitiligo ( 20526339)
Protein-Protein Interactions		4 interactors: CEP19 NAGK PPP2R1B VASP	13 interactors: AK4 CALCOCO1 CCDC102B CREB3L2 FGFR1OP KIAA1958 KXD1 RABL2A RABL2B REL SYNE4 VCP ZBTB14
Entrez ID		11116	84984
HPRD ID		10392	17488
Ensembl ID			ENSG00000174007
Uniprot IDs		B4DH64 O95684	Q96LK0
PDB IDs		2D68
Enriched GO Terms of Interacting Partners?		N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process N-acetylneuraminate Metabolic Process	Rab Protein Signal Transduction Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Establishment Of Epithelial Cell Apical/basal Polarity Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Cellular Protein Localization Regulation Of Protein Deubiquitination Cellular Localization Protein Hexamerization ADP Biosynthetic Process Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Transport Ras Protein Signal Transduction Establishment Of Monopolar Cell Polarity Aggresome Assembly Translesion Synthesis Nucleoside Diphosphate Biosynthetic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Golgi Vesicle Transport ADP Metabolic Process
Tagcloud ?		aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Difference) ?		aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Intersection) ?