ATG4D and TIMM29

		ATG4D	TIMM29
Description		autophagy related 4D cysteine peptidase	translocase of inner mitochondrial membrane 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity Cysteine-type Exopeptidase Activity	Protein Binding Protein Transporter Activity
	Biological Process	Autophagosome Assembly Mitophagy Proteolysis Autophagy Apoptotic Process Protein Transport Protein Processing Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation	Protein Transport Protein Insertion Into Mitochondrial Inner Membrane
Pathways		Macroautophagy
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: CASP3 CASP8 GABARAP GABARAPL1 GABARAPL2 MAP1LC3B TRIM55	2 interacting genes: APOE MAILR
Entrez ID		84971	90580
HPRD ID		07005	14275
Ensembl ID		ENSG00000130734	ENSG00000142444
Uniprot IDs		B4DGM8 Q86TL0	Q9BSF4
PDB IDs			7CGP
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Autophagosome Maturation Vacuole Organization Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Ubiquitin Protein Ligase Binding Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Beta-tubulin Binding Cellular Response To Starvation Response To Starvation Response To Anesthetic Cellular Response To Nutrient Levels Death-inducing Signaling Complex Organelle Assembly Autophagy Positive Regulation Of Pyroptotic Inflammatory Response Response To Cobalt Ion Microtubule Death Receptor Binding Response To Nutrient Levels Response To Stress Execution Phase Of Apoptosis Pyroptotic Inflammatory Response Microtubule Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Organization Cellular Response To Stress Apoptotic Signaling Pathway Cytoplasmic Vesicle Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Regulation Of Proteolysis Catabolic Process Phospholipase A2 Activator Activity Response To Estradiol Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Positive Regulation Of Protein K48-linked Ubiquitination Axoneme Cysteine-type Peptidase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Phospholipid Efflux Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of RNA Biosynthetic Process Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Presynaptic Membrane Organization Regulation Of Nucleobase-containing Compound Metabolic Process Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Zinc Ion Binding DNA Binding Intermediate-density Lipoprotein Particle Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipoprotein Transport Negative Regulation Of Dendritic Spine Maintenance Very-low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Very-low-density Lipoprotein Particle Clearance Multivesicular Body, Internal Vesicle Positive Regulation Of Phospholipid Efflux Positive Regulation Of Amyloid Fibril Formation AMPA Glutamate Receptor Clustering NMDA Glutamate Receptor Clustering Positive Regulation Of Inclusion Body Assembly Triglyceride-rich Lipoprotein Particle Clearance Positive Regulation Of Dendritic Spine Maintenance Regulation Of Plasma Lipoprotein Particle Levels Chylomicron Remnant Clearance Protein-phosphatidylethanolamide Deconjugating Activity Cysteine-type Exopeptidase Activity Protein Delipidation Regulation Of Peroxisome Size Regulation Of Neurofibrillary Tangle Assembly Lipoprotein Biosynthetic Process Phosphatidylcholine-sterol O-acyltransferase Activator Activity Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
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