TRIM51 and RNF40

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM51	RNF40
Gene Name		tripartite motif-containing 51	ring finger protein 40, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane HULC Complex Neuron Projection
	Molecular Function	Zinc Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Syntaxin-1 Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Histone H2B Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MAGEA11 RNF40 SPRY2	18 interactors: AMOTL2 ATM CCDC146 CDC73 HIST2H2BE ITSN1 MSL1 NCBP1 RB1 SFR1 TRIM51 UBE2A UBE2B UBE2E1 UBE2I UBE2L6 WAC ZNF451
Entrez ID		84767	9810
HPRD ID		10282	07411
Ensembl ID		ENSG00000124900	ENSG00000103549
Uniprot IDs		Q9BSJ1	A8K6K1 F8W8Z4 O75150
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lung Growth Histone H2B Ubiquitination Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Ras GTPase Activity Histone Monoubiquitination Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Branch Elongation Of An Epithelium Negative Regulation Of GTPase Activity Histone Ubiquitination Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Protein Monoubiquitination Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of ERBB Signaling Pathway Spindle Localization Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Organ Growth Inner Ear Morphogenesis Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity	Histone Ubiquitination Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Protein Monoubiquitination Histone H2B Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone Monoubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition ISG15-protein Conjugation Organelle Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Proteasomal Protein Catabolic Process Regulation Of Chromosome Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Chromosome Organization Cell Cycle Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone H2A Ubiquitination Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Negative Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Mitotic Nuclear Division Catabolic Process Histone MRNA Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Postreplication Repair
Tagcloud ?			accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Difference) ?			accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Intersection) ?