FAM156A and CRACR2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM156A	CRACR2A
Description		family with sequence similarity 156 member A	calcium release activated channel regulator 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Membrane	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		7 interacting genes: ATRIP CRACR2A GADD45G MAGEA11 SAT1 TEX11 TFIP11	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		29057	84766
HPRD ID		06683	10079
Ensembl ID		ENSG00000268350	ENSG00000130038
Uniprot IDs		Q8NDB6	Q9BSW2
PDB IDs			6PSD
Enriched GO Terms of Interacting Partners?		Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding Positive Regulation Of JNK Cascade Spliceosomal Complex Disassembly Gene Conversion Meiotic Gene Conversion ATR-ATRIP Complex Diamine N-acetyltransferase Activity U2-type Post-mRNA Release Spliceosomal Complex Male Meiosis Chromosome Segregation Polyamine Catabolic Process Regulation Of JNK Cascade Regulation Of Double-strand Break Repair DNA Metabolic Process Chiasma Assembly Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Weibel-Palade Body Spermidine Metabolic Process Putrescine Metabolic Process Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Protection From Non-homologous End Joining At Telomere Central Element Regulation Of DNA Repair Store-operated Calcium Entry Response To Histamine	Identical Protein Binding
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