CNDP1 and CNDP2

Number of citations of the paper that reports this interaction (PMID 12473676)
25

Data Source:
HPRD (in vitro)

		CNDP1	CNDP2
Gene Name		carnosine dipeptidase 1 (metallopeptidase M20 family)	CNDP dipeptidase 2 (metallopeptidase M20 family)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Carboxypeptidase Activity Metallopeptidase Activity Dipeptidase Activity Tripeptidase Activity Metal Ion Binding	Carboxypeptidase Activity Metallopeptidase Activity Dipeptidase Activity Tripeptidase Activity Metal Ion Binding
	Biological Process	Proteolysis	Sulfur Amino Acid Metabolic Process Proteolysis Glutathione Biosynthetic Process Xenobiotic Metabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways			Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Sulfur amino acid metabolism Glutathione synthesis and recycling Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Metabolism of amino acids and derivatives Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS			Refractive error ( 23396134)
Protein-Protein Interactions		2 interactors: APP CNDP2	3 interactors: CNDP1 NDRG1 ZDHHC17
Entrez ID		84735	55748
HPRD ID		09894	09893
Ensembl ID		ENSG00000150656	ENSG00000133313
Uniprot IDs		Q96KN2	Q96KP4
PDB IDs		3DLJ
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Glutathione Biosynthetic Process Glutathione Derivative Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Peptide Biosynthetic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Sulfur Amino Acid Metabolic Process Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Glutathione Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing	Positive Regulation Of Spindle Checkpoint Positive Regulation Of Cell Cycle Checkpoint Peripheral Nervous System Myelin Maintenance Lipoprotein Transport Magnesium Ion Transport Regulation Of Spindle Checkpoint Myelin Maintenance Protein Palmitoylation Mast Cell Activation Regulation Of Cell Cycle Checkpoint Myelination In Peripheral Nervous System Schwann Cell Development
Tagcloud ?			alphascreen ammp calnexin combines hsp90aa1 hsp90b1 hspa1b hspa5 hspa9 identifier imbalance itraq nfhcc nonfibrotic nontumor p4hb pdia6 phosphoproteomics pointed proteomexchange proteomics proteostasis pxd001253 resident ser583 txn ubc unraveling vcp
Tagcloud (Difference) ?			alphascreen ammp calnexin combines hsp90aa1 hsp90b1 hspa1b hspa5 hspa9 identifier imbalance itraq nfhcc nonfibrotic nontumor p4hb pdia6 phosphoproteomics pointed proteomexchange proteomics proteostasis pxd001253 resident ser583 txn ubc unraveling vcp
Tagcloud (Intersection) ?