MCEE and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		MCEE	CMTM5
Description		methylmalonyl-CoA epimerase	CKLF like MARVEL transmembrane domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Space Membrane
	Molecular Function	Methylmalonyl-CoA Epimerase Activity Protein Binding Isomerase Activity Metal Ion Binding	Cytokine Activity Protein Binding
	Biological Process	Short-chain Fatty Acid Catabolic Process L-methylmalonyl-CoA Metabolic Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways		Propionyl-CoA catabolism
Drugs
Diseases		Methylmalonic aciduria (MMA)
GWAS		Erythema nodosum in inflammatory bowel disease ( 24487271) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: AGTRAP APP CD81 CMTM5 STX8	133 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPR42 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SCN3B SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35H1 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		84693	116173
HPRD ID		12229	06986
Ensembl ID		ENSG00000124370	ENSG00000166091
Uniprot IDs		Q96PE7	Q96DZ9
PDB IDs		3RMU 6QH4
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Integrin Binding Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Cell Recognition Perinuclear Region Of Cytoplasm Axon Midline Choice Point Recognition Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Regulation Of Mononuclear Cell Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Macrophage Fusion Vesicle Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Regulation Of Protein Localization To Membrane Myoblast Fusion Involved In Skeletal Muscle Regeneration Angiotensin Type II Receptor Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway MHC Class II Protein Binding Osteoclast Fusion Myosin Phosphatase Regulator Activity Positive Regulation Of Protein Catabolic Process	Protein Binding Mitochondrion Mitochondrial Matrix Phosphatidylcholine-sterol O-acyltransferase Activator Activity Identical Protein Binding Lipid Binding Succinate Metabolic Process Mitochondrial Outer Membrane Membrane Endoplasmic Reticulum Membrane Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Chylomicron Phospholipid Efflux Small Molecule Biosynthetic Process Low-density Lipoprotein Particle Regulation Of Mitochondrion Organization Regulation Of Release Of Cytochrome C From Mitochondria Endoplasmic Reticulum-autophagosome Adaptor Activity Phospholipid Binding Ligase Activity
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