CCKAR

Gene Name		cholecystokinin A receptor
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Cholecystokinin Receptor Activity Peptide Binding
	Biological Process	Neuron Migration Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Axonogenesis Response To Nutrient Digestion Feeding Behavior Forebrain Development Cellular Response To Hormone Stimulus Cholecystokinin Signaling Pathway Regulation Of Hormone Secretion Response To Peptide
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Ceruletide
Diseases
GWAS
Protein-protein Interactions		3 interactors: CCK CCKBR PPP1R9B
Entrez ID		886
HPRD ID		00322
Ensembl ID		ENSG00000163394
Uniprot IDs		P32238
PDB IDs		1D6G 1HZN 1PB2
Enriched GO Terms of Interacting Partners?		Feeding Behavior Regulation Of Phosphorylation Regulation Of Opioid Receptor Signaling Pathway Cholecystokinin Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Cellular Response To Morphine Regulation Of Cell Growth By Extracellular Stimulus Cellular Response To Isoquinoline Alkaloid Regulation Of Catalytic Activity Response To Extracellular Stimulus Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Appetite Gastric Acid Secretion Regulation Of Exit From Mitosis Behavior Filopodium Assembly Regulation Of Mitochondrial Depolarization Regulation Of Response To Food Positive Regulation Of Protein Oligomerization Cellular Response To Ammonium Ion Regulation Of Appetite Regulation Of Sensory Perception Of Pain Neuron Projection Development Regulation Of Protein Oligomerization Positive Regulation Of Cell Proliferation Cell Migration Eating Behavior Release Of Cytochrome C From Mitochondria Cell Motility Regulation Of Membrane Depolarization Behavioral Fear Response Neuron Development Cellular Response To Alkaloid Response To Morphine Fear Response System Development Regulation Of Protein Phosphorylation Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Differentiation G-protein Coupled Receptor Signaling Pathway Cell Projection Organization Regulation Of Neurological System Process Regulation Of Lipid Kinase Activity Acid Secretion Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Locomotion Multicellular Organismal Development Anatomical Structure Development
Tagcloud ?		afferent amphetamine cart cascades coadministration cocaine colocalization egr electroporation feeding firing ganglia hairpin hypothalamus lentiviral leptin lrbs mediating neurotransmitter ng nodose ope satiety short silencing synergistically vagal