DYRK3 and ZNF350

Number of citations of the paper that reports this interaction (PubMedID 36585413)
42

Data Source:
BioGRID (two hybrid)

		DYRK3	ZNF350
Description		dual specificity tyrosine phosphorylation regulated kinase 3	zinc finger protein 350
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Stress Granule Nuclear Speck	Nucleus Nucleoplasm Nuclear Matrix Nuclear Body Transcription Repressor Complex
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Phosphorylation Erythrocyte Differentiation Nuclear Speck Organization Stress Granule Disassembly Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Division Regulation Of Cellular Response To Stress Positive Regulation Of Cell Cycle G2/M Phase Transition Organelle Disassembly Regulation Of TORC1 Signaling	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways			Generic Transcription Pathway SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Tourette syndrome ( 30818990)
Interacting Genes		12 interacting genes: ACAA2 ADAM22 DNAJA2 DNAJB1 FBXO25 GORASP2 MAGI2 NEDD4L PGM1 PRNP SNAPIN ZNF350	9 interacting genes: ATF7IP BRCA1 DYRK3 FBXL17 NEK1 RCAN1 RNF11 TIAM1 USP21
Entrez ID		8444	59348
HPRD ID		04607	05663
Ensembl ID		ENSG00000143479	ENSG00000256683
Uniprot IDs		O43781	Q9GZX5
PDB IDs		5Y86
Enriched GO Terms of Interacting Partners?		Protein-folding Chaperone Binding	Protein Modification Process Pericentriolar Material Epigenetic Regulation Of Gene Expression Post-translational Protein Modification Protein Autoubiquitination Organelle Disassembly Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex
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