TMEM246 and B3GNT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TMEM246	B3GNT2
Gene Name		transmembrane protein 246	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		Galactosyltransferase Activity N-acetyllactosaminide Beta-1,3-N-acetylglucosaminyltransferase Activity
	Biological Process		Carbohydrate Metabolic Process Protein O-linked Glycosylation Axon Guidance Sensory Perception Of Smell Biological_process Pathogenesis O-glycan Processing Keratan Sulfate Biosynthetic Process Glycosaminoglycan Metabolic Process Poly-N-acetyllactosamine Biosynthetic Process Keratan Sulfate Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome Keratan sulfate/keratin metabolism MPS IX - Natowicz syndrome Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism O-linked glycosylation Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases Defective CHST6 causes MCDC1 MPS IIID - Sanfilippo syndrome D MPS IIIC - Sanfilippo syndrome C Keratan sulfate biosynthesis Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Post-translational protein modification Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS Metabolism of carbohydrates MPS VII - Sly syndrome O-linked glycosylation of mucins MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 20062062) Rheumatoid arthritis ( 22446963)
Protein-Protein Interactions		1 interactors: B3GNT2	2 interactors: C1GALT1C1 TMEM246
Entrez ID		84302	10678
HPRD ID		12940	09279
Ensembl ID			ENSG00000170340
Uniprot IDs		Q9BRR3	Q9NY97
PDB IDs
Enriched GO Terms of Interacting Partners?		Poly-N-acetyllactosamine Biosynthetic Process Poly-N-acetyllactosamine Metabolic Process Keratan Sulfate Biosynthetic Process Keratan Sulfate Metabolic Process Cellular Polysaccharide Biosynthetic Process Polysaccharide Biosynthetic Process O-glycan Processing Polysaccharide Metabolic Process Protein O-linked Glycosylation Glycosaminoglycan Biosynthetic Process Carbohydrate Biosynthetic Process Glycosaminoglycan Metabolic Process Post-translational Protein Modification Pathogenesis Cellular Carbohydrate Metabolic Process Macromolecule Glycosylation Protein Glycosylation Glycosylation Sulfur Compound Metabolic Process Sensory Perception Of Smell Axon Guidance Glycoprotein Biosynthetic Process	Platelet Morphogenesis
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