PGAP4 and B3GNT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PGAP4	B3GNT2
Description		post-GPI attachment to proteins GalNAc transferase 4	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Transferase Activity Glycosyltransferase Activity	Protein Binding N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity N-acetyllactosaminide Beta-1,3-N-acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process	Protein Glycosylation Protein O-linked Glycosylation Axon Guidance Sensory Perception Of Smell Protein O-linked Glycosylation Via N-acetyl-galactosamine Keratan Sulfate Proteoglycan Biosynthetic Process Poly-N-acetyllactosamine Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways			Keratan sulfate biosynthesis O-linked glycosylation of mucins
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 20062062) Blood protein levels ( 30072576) Coronary artery disease in type 1 diabetes ( 32077919) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Psoriasis ( 23143594 25903422) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 22446963 24390342 30423114)
Interacting Genes		4 interacting genes: B3GNT2 FBXO7 GOLPH3 GOLPH3L	2 interacting genes: C1GALT1C1 PGAP4
Entrez ID		84302	10678
HPRD ID		12940	09279
Ensembl ID		ENSG00000165152	ENSG00000170340
Uniprot IDs		Q9BRR3	Q9NY97
PDB IDs			6WMM 6WMN 6WMO 7JHK 7JHL 7JHM 7JHN 7JHO 8SZ3 8TIC 8TJC
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Protein Targeting Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Establishment Of Protein Localization To Organelle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Golgi Membrane Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Lewy Body Core Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Localization To Plasma Membrane Glycoprotein Biosynthetic Process Establishment Of Protein Localization To Membrane Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery N-acetyllactosaminide Beta-1,3-N-acetylglucosaminyltransferase Activity Positive Regulation Of Protein Transport Glycoprotein Metabolic Process Poly-N-acetyllactosamine Biosynthetic Process Regulation Of Protein Secretion Response To Rapamycin Establishment Of Protein Localization Golgi Vesicle Transport Poly-N-acetyllactosamine Metabolic Process Golgi Apparatus Positive Regulation Of Secretion By Cell Protein Localization To Membrane Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Lipid Binding Golgi Ribbon Formation	Cell Morphogenesis Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Regulation Of Embryonic Cell Shape Axonemal Basal Plate Platelet Morphogenesis Septin Cytoskeleton Organization Tongue Morphogenesis Auditory Receptor Cell Morphogenesis Podocyte Cell Migration Respiratory System Development Digestive System Development Carbohydrate Derivative Biosynthetic Process Golgi Membrane Establishment Of Planar Polarity Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Establishment Of Cell Polarity Circulatory System Development Regulation Of Establishment Or Maintenance Of Cell Polarity GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Regulation Of Ruffle Assembly Carbohydrate Derivative Metabolic Process Epithelial Cell Migration Regulation Of Fibroblast Migration Neural Tube Development Intraciliary Transport
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