TRAPPC2B and TRAPPC3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TRAPPC2B	TRAPPC3
Description		trafficking protein particle complex subunit 2B	trafficking protein particle complex subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Cis-Golgi Network Membrane TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	Transcription Corepressor Binding Protein Binding Transcription Regulator Inhibitor Activity	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Positive Regulation Of Gene Expression Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Golgi Vesicle Transport COPII Vesicle Coating Vesicle Tethering
Pathways			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			Palmitic Acid Myristic acid S-palmitoyl-L-cysteine
Diseases
GWAS			Glaucoma (primary open-angle) ( 33627673) Intraocular pressure ( 30054594)
Interacting Genes		19 interacting genes: EPS15L1 INCA1 JOSD2 KCTD1 LSM3 MBD3L1 NICN1 NME4 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC5 TRIM42 UQCC2 ZBED1 ZNF438 ZNF655 ZRANB1	8 interacting genes: APP CDC45 LIG4 PLEKHF2 TRAPPC2 TRAPPC2B TRAPPC2L TRAPPC6A
Entrez ID		10597	27095
HPRD ID			11644
Ensembl ID		ENSG00000256060	ENSG00000054116
Uniprot IDs		P0DI82	A0A087WWM0 A0A087WYS5 O43617
PDB IDs			1SZ7 2C0J 2CFH 3KXC
Enriched GO Terms of Interacting Partners?		TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Deubiquitinase Activity Vesicle Tethering Intermembrane Phospholipid Transfer Protein Autosumoylation Vesicle Coating TRAPPI Protein Complex Coated Vesicle Membrane	TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Vesicle Tethering Vesicle Coating TRAPPII Protein Complex Vesicle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Transport Vesicle-mediated Transport Protein-containing Complex Assembly Golgi Vesicle Transport Protein-containing Complex Organization Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell Cellular Component Assembly Perinuclear Region Of Cytoplasm Organelle Organization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Establishment Of Integrated Proviral Latency Mitotic DNA Replication Preinitiation Complex Assembly Endoplasmic Reticulum-Golgi Intermediate Compartment Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Establishment Of Viral Latency DNA Replication Preinitiation Complex PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization DNA Ligase (ATP) Activity DNA Ligase IV Complex DNA Ligase Activity DNA Replication Preinitiation Complex Assembly Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling
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