TRAPPC2B and ZBED1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		TRAPPC2B	ZBED1
Description		trafficking protein particle complex subunit 2B	zinc finger BED-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane
	Molecular Function	Transcription Corepressor Binding Protein Binding Transcription Regulator Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Zinc Ion Binding Transferase Activity SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Positive Regulation Of Gene Expression Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Host-mediated Suppression Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation
Pathways			SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: EPS15L1 INCA1 JOSD2 KCTD1 LSM3 MBD3L1 NICN1 NME4 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC5 TRIM42 UQCC2 ZBED1 ZNF438 ZNF655 ZRANB1	61 interacting genes: AIRIM AMOTL2 ATRX CBX4 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS1 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RANBP9 RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO1 SUMO2 TDP2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2 ZHX1 ZNF451
Entrez ID		10597	9189
HPRD ID			02170
Ensembl ID		ENSG00000256060	ENSG00000214717
Uniprot IDs		P0DI82	O96006
PDB IDs			2CT5
Enriched GO Terms of Interacting Partners?		TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Deubiquitinase Activity Vesicle Tethering Intermembrane Phospholipid Transfer Protein Autosumoylation Vesicle Coating TRAPPI Protein Complex Coated Vesicle Membrane	Protein Sumoylation PML Body SUMO Transferase Activity SUMO Ligase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Presynaptic Cytosol Postsynaptic Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Corepressor Activity Negative Regulation Of Metabolic Process Post-translational Protein Modification Protein Binding DNA Repair Ubiquitin Protein Ligase Binding Organelle Organization Small Protein Activating Enzyme Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Stress Nuclear Body Regulation Of Ubiquitin-dependent Protein Catabolic Process DNA Damage Response Protein Modification Process Nucleoplasm Enzyme Binding Error-prone Translesion Synthesis Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cytoplasm RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nucleotide-activated Protein Kinase Complex Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Response To Radiation Response To Light Stimulus Regulation Of RNA Metabolic Process Microtubule Cytoskeleton Organization Nucleus DNA Metabolic Process
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