POMK and IER3IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POMK	IER3IP1
Description		protein O-mannose kinase	immediate early response 3 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Phosphotransferase Activity, Alcohol Group As Acceptor Carbohydrate Kinase Activity	Protein Binding
	Biological Process	Protein O-linked Glycosylation Brain Development Learning Or Memory Sensory Perception Of Pain Carbohydrate Phosphorylation Neuromuscular Process	Type B Pancreatic Cell Differentiation Positive Regulation Of Extracellular Matrix Constituent Secretion Chromatin Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Brain Development Negative Regulation Of Cell Population Proliferation Gene Expression Protein Transport Organ Growth Glucose Homeostasis Negative Regulation Of Apoptotic Process Cell Maturation Positive Regulation Of Protein Secretion Insulin Metabolic Process Regulation Of Fibroblast Apoptotic Process
Pathways		DAG1 core M3 glycosylations
Drugs
Diseases
GWAS			Fruit consumption ( 32066663)
Interacting Genes		6 interacting genes: BMPR1B IER3IP1 MS4A13 OGT TGFBR1 UBC	43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27
Entrez ID		84197	51124
HPRD ID		08668	13727
Ensembl ID		ENSG00000185900	ENSG00000134049
Uniprot IDs		Q9H5K3	Q9Y5U9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Activity, Type I Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Extracellular Matrix Organization Endothelial Cell Proliferation Regulation Of Chondrocyte Differentiation SMAD Binding Regulation Of Cartilage Development Protein Metabolic Process Regulation Of Extracellular Matrix Organization Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Cell Population Proliferation HFE-transferrin Receptor Complex Regulation Of Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Receptor Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Negative Regulation Of Chondrocyte Proliferation Glycoprotein Biosynthetic Process BMP Receptor Activity Macromolecule Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Macromolecule Biosynthetic Process Ovarian Cumulus Expansion Endochondral Bone Morphogenesis Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Myofibroblast Differentiation Activin Receptor Complex Activin Receptor Activity, Type I Epithelial Cell Proliferation Regulation Of Protein Ubiquitination Ventricular Compact Myocardium Morphogenesis Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Parathyroid Gland Development Positive Regulation Of Tight Junction Disassembly Germ Cell Migration Vascular Endothelial Cell Proliferation Transforming Growth Factor Beta Receptor Activity Epicardium Morphogenesis Trophoblast Cell Migration Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Ligand-receptor Complex Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbohydrate Homeostasis Non-canonical Inflammasome Complex Assembly Glucose Homeostasis Positive Regulation Of Transcription By Glucose	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipid Biosynthetic Process Sphingosine N-acyltransferase Activity Membrane Lipid Metabolic Process Lipid Metabolic Process Response To Endoplasmic Reticulum Stress
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