CIAO2A and SETD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIAO2A	SETD4
Description		cytosolic iron-sulfur assembly component 2A	SET domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytosolic [4Fe-4S] Assembly Targeting Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity Histone Methyltransferase Activity Histone H4K20 Methyltransferase Activity Histone H3K4 Methyltransferase Activity Histone H3K36 Methyltransferase Activity Histone H4K20me Methyltransferase Activity Histone H4K20 Monomethyltransferase Activity Histone H3K4 Monomethyltransferase Activity
	Biological Process	Chromosome Segregation Protein Maturation	Chromatin Remodeling Inflammatory Response Methylation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Inflammatory Response Regulation Of Cell Proliferation In Bone Marrow
Pathways
Drugs
Diseases
GWAS			Asthma (adult onset) ( 31036433) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Obesity-related traits ( 23251661)
Interacting Genes		25 interacting genes: AGTRAP APOA2 CIAO1 CMTM6 CREB3L1 DERL1 DGAT2L6 EBAG9 ERGIC3 FKBP7 GJA8 GSC2 KCNIP1 LIME1 MEST PLP2 PLPP6 PLPPR2 PRAF2 RHBDD2 SETD4 SIN3A TMED8 TNFRSF10D VAMP3	1 interacting genes: CIAO2A
Entrez ID		84191	54093
HPRD ID		08010	10743
Ensembl ID		ENSG00000166797	ENSG00000185917
Uniprot IDs		Q9H5X1	A8MTS1 Q9NVD3
PDB IDs		2M5H 3UX2 3UX3
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Signal Recognition Particle Binding Endoplasmic Reticulum Endoplasmic Reticulum Unfolded Protein Response Phosphatidate Phosphatase Activity
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