TOMM40L and CD244

		TOMM40L	CD244
Description		translocase of outer mitochondrial membrane 40 like	CD244 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Protein-containing Complex Pore Complex	Plasma Membrane External Side Of Plasma Membrane Membrane Membrane Raft
	Molecular Function	Molecular_function Protein Transmembrane Transporter Activity Porin Activity	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Monoatomic Ion Transport Biological_process Protein Transport Protein Import Into Mitochondrial Matrix Transmembrane Transport	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Immune System Process Immune Response Signal Transduction Natural Killer Cell Activation Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: RAB1B	5 interacting genes: ARHGEF7 CD247 CD48 LAT SH2D1B
Entrez ID		84134	51744
HPRD ID		13354	16121
Ensembl ID		ENSG00000158882	ENSG00000122223
Uniprot IDs		Q969M1	Q9BZW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Granzyme B Production Natural Killer Cell Activation Involved In Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process External Side Of Plasma Membrane Virion Assembly Establishment Of Endothelial Intestinal Barrier	Cell Activation Leukocyte Activation Adaptive Immune Response Lymphocyte Activation Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response Immune Response Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Immunity Platelet-derived Growth Factor Alpha-receptor Activity Negative Regulation Of Microtubule Nucleation Aconitate Hydratase Activity Fc-gamma Receptor III Complex Gamma-delta T Cell Receptor Complex Immune Effector Process Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Phospholipase C Activator Activity Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Metanephric Glomerular Capillary Formation Platelet-derived Growth Factor Receptor-ligand Complex TCR Signalosome
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