TSSK6 and SSBP1

		TSSK6	SSBP1
Description		testis specific serine kinase 6	single stranded DNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal Microtubule Doublet Inner Sheath	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity	DNA Binding Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding Enzyme Activator Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation Flagellated Sperm Motility Sperm DNA Condensation	DNA Replication DNA-templated DNA Replication Positive Regulation Of Helicase Activity Protein Homotetramerization Positive Regulation Of Mitochondrial DNA Replication
Pathways			Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation Strand-asynchronous mitochondrial DNA replication
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Percent liver fat ( 34128465) Refractive error ( 32231278) Schizophrenia ( 23974872 25056061 29483656)	Anorexia nervosa ( 23568457)
Interacting Genes		8 interacting genes: APP H2AC20 H2AX H3C1 HSP90AB1 HSPA1A HSPA8 MBP	13 interacting genes: CDK1 CEBPA CKS1B CKS2 FOXP1 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG TP53 YWHAQ
Entrez ID		83983	6742
HPRD ID		15441	02703
Ensembl ID		ENSG00000178093	ENSG00000106028
Uniprot IDs		A0A024R7Q5 Q9BXA6	A4D1U3 B7Z268 Q04837
PDB IDs			1S3O 2DUD 3ULL 6RUP 8UZT
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Import Extracellular Exosome ATP-dependent Protein Folding Chaperone C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Protein Folding Chaperone Heat Shock Protein Binding G Protein-coupled Receptor Binding Protein-containing Complex Organization Structural Constituent Of Chromatin Response To Unfolded Protein Epigenetic Regulation Of Gene Expression Cadherin Binding Unfolded Protein Binding Cellular Component Assembly Protein Heterodimerization Activity Nucleosome Ficolin-1-rich Granule Lumen Receptor Ligand Activity Chaperone-mediated Protein Complex Assembly Regulation Of Macromolecule Metabolic Process Enzyme Binding Regulation Of Proteolysis Protein-containing Complex Protein-containing Complex Assembly Disordered Domain Specific Binding MHC Class II Protein Complex Binding Protein Refolding Protein Folding Chaperone Complex COP9 Signalosome Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Proteolysis Positive Regulation Of Nitric Oxide Metabolic Process Protein Folding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Cellular Response To Heat Chaperone-mediated Autophagy Translocation Complex Disassembly Positive Regulation Of Metalloendopeptidase Activity Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Chromatin Remodeling Acetylcholine Receptor Activator Activity Positive Regulation Of Metabolic Process	Chromatin Binding Fibroblast Proliferation Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleobase-containing Compound Biosynthetic Process Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Mitochondrial DNA Metabolic Process Core Promoter Sequence-specific DNA Binding Negative Regulation Of Stem Cell Proliferation DNA-templated Transcription Protein-containing Complex Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity 14-3-3 Protein Binding Regulation Of RNA Metabolic Process Pronuclear Fusion Mitotic DNA-templated DNA Replication Regulation Of DNA-templated Transcription Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Cell Differentiation Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic DNA Integrity Checkpoint Signaling Cyclin B1-CDK1 Complex Macromolecule Biosynthetic Process Cell Population Proliferation Cyclin A1-CDK1 Complex Regulation Of Heart Growth DNA-templated DNA Replication DNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Cyclin A2-CDK1 Complex Cyclin-dependent Protein Kinase Activity Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell Cycle Transcription Regulator Complex Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Stem Cell Proliferation Regulation Of Stem Cell Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mononuclear Cell Differentiation Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 C/EBP Complex SCF Ubiquitin Ligase Complex DNA Replication Proofreading
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