RASSF4 and CENPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASSF4	CENPH
Description		Ras association domain family member 4	centromere protein H
Image		No pdb structure
GO Annotations	Cellular Component		Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	Protein Binding	Protein Binding Kinetochore Binding
	Biological Process	Signal Transduction	Mitotic Spindle Organization Chromosome Segregation Kinetochore Assembly Kinetochore Organization
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis ( 31749835)
Interacting Genes		7 interacting genes: CENPH DLG4 HGS HMGB1 IFT20 MAGEA6 STK3	19 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 CRYAA DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NUF2 NUP54 RASSF4 SPAG5 UBC ZNF493 ZSCAN12
Entrez ID		83937	64946
HPRD ID		15219	12029
Ensembl ID		ENSG00000107551	ENSG00000153044
Uniprot IDs		Q9H2L5	A0A0S2Z5T0 Q9H3R5
PDB IDs			7PB4 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Protein Localization To Organelle Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Membrane P2Y1 Nucleotide Receptor Binding Negative Regulation Of Endocytosis Neuron Projection Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Positive Regulation Of Myeloid Progenitor Cell Differentiation Organelle Organization Neuron Projection Development Establishment Of Protein Localization Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Localization Within Membrane Cellular Component Assembly Regulation Of Vesicle-mediated Transport C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Mismatch Repair Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Cell Clearance ESCRT-0 Complex Kinociliary Basal Body Opsin Transport Intraciliary Transport Particle Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Localization AMPA Glutamate Receptor Clustering NMDA Selective Glutamate Receptor Signaling Pathway Learning Establishment Or Maintenance Of Cell Polarity Neuroligin Family Protein Binding Regulation Of Mismatch Repair Negative Regulation Of DNA-templated Transcription Initiation Regulation Of JNK Cascade Epithelial Cell Proliferation Plasmacytoid Dendritic Cell Activation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Supercoiled DNA Binding Cell Population Proliferation Positive Regulation Of Dendritic Cell Differentiation Neutrophil Clearance	Lens Fiber Cell Morphogenesis Kinetochore Nuclear Chromosome Segregation Cytoskeleton Organization Protein Localization To Nuclear Envelope Microtubule Cytoskeleton Organization Nucleus Organization Microtubule-based Process Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Localization To Centrosome Microtubule Plus-end Chromosome Segregation Organelle Organization Spindle Organization Chromosome, Centromeric Region Mitotic Sister Chromatid Segregation Attachment Of Spindle Microtubules To Kinetochore Sister Chromatid Segregation Cell Morphogenesis Nucleoside Metabolic Process Midbody S-methyl-5-thioadenosine Phosphorylase Activity Mitotic Metaphase Chromosome Alignment Protein Localization To Cytoskeleton Organelle Localization Structural Constituent Of Nuclear Lamina Nicotinamide Riboside Catabolic Process Zonula Adherens Assembly Metaphase Chromosome Alignment Regulation Of Cellular Localization Microtubule Binding Establishment Of Organelle Localization Protein Localization To Nuclear Inner Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?