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MICB
Gene Name
MHC class I polypeptide-related sequence B
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Antigen Binding
Beta-2-microglobulin Binding
Natural Killer Cell Lectin-like Receptor Binding
Biological Process
T Cell Mediated Cytotoxicity
Immune Response-activating Cell Surface Receptor Signaling Pathway
Response To Oxidative Stress
Response To Heat
Viral Process
Cytolysis
Antigen Processing And Presentation
Response To Retinoic Acid
Natural Killer Cell Mediated Cytotoxicity
Gamma-delta T Cell Activation
Negative Regulation Of Defense Response To Virus By Host
Regulation Of Immune Response
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Adaptive Immune System
Drugs
Diseases
GWAS
AIDS progression (
19115949
)
Behcet's disease (
23001997
)
Crohn's disease (
23128233
)
Dengue shock syndrome (
22001756
)
Hodgkin's lymphoma (
22286212
)
Metabolic syndrome (
22399527
)
Pulmonary function (
21946350
)
Protein-protein Interactions
2 interactors:
KLRC4
KLRK1
Entrez ID
4277
HPRD ID
03894
Ensembl ID
ENSG00000204516
Uniprot IDs
A2AC57
F5H7Q8
Q29980
Q861E6
PDB IDs
1JE6
2WY3
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Defense Response
Cellular Defense Response
Natural Killer Cell Activation
T Cell Costimulation
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of Cell Killing
Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of Innate Immune Response
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Regulation Of Innate Immune Response
Response To Stress
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Tagcloud
?
aberrantly
allogeneic
autologous
axis
bcsc
bcscs
cytotoxicity
downregulation
elusive
escape
failed
infiltrating
killer
killing
limit
metastasis
mica
mir20a
nk
nkg2d
oncogenic
promoted
restored
resultant
rich
sensitized
stimulatory
thereby
trans