RAB1B and MICAL3

Number of citations of the paper that reports this interaction (PMID 15694364)
20

Data Source:
HPRD (in vitro, two hybrid)

		RAB1B	MICAL3
Gene Name		RAB1B, member RAS oncogene family	microtubule associated monooxygenase, calponin and LIM domain containing 3
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrion Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Pre-autophagosomal Structure Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Actin Binding Zinc Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Rab GTPase Binding FAD Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Autophagy Virion Assembly Rab Protein Signal Transduction Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly	Exocytosis Cytoskeleton Organization Actin Filament Depolymerization Oxidation-reduction Process
Pathways		Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Presence of antiphospholipid antibodies ( 23509613)
Protein-Protein Interactions		10 interactors: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RUSC2 SMARCC2 TOMM40L	1 interactors: RAB1B
Entrez ID		81876	57553
HPRD ID		11469	19352
Ensembl ID		ENSG00000174903	ENSG00000243156
Uniprot IDs		E9PLD0 Q9H0U4	Q7RTP6
PDB IDs		3JZA 3NKV 4HLQ 4I1O	2D88
Enriched GO Terms of Interacting Partners?		Actin Filament Depolymerization Protein Complex Disassembly Actin Polymerization Or Depolymerization Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Protein Targeting To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Protein Complex Disassembly Axon Choice Point Recognition Sulfur Oxidation Negative Regulation Of Neuron Differentiation Protein Geranylgeranylation	Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Vacuole Organization Virion Assembly Rab Protein Signal Transduction ER To Golgi Vesicle-mediated Transport Regulation Of Autophagy Autophagy Viral Life Cycle Ras Protein Signal Transduction Golgi Vesicle Transport
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