RAB1B

Description		RAB1B, member RAS oncogene family
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Membrane Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Golgi Organization Protein Transport Virion Assembly Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		12 interacting genes: APP CHM FNDC3B GDI1 GOLGA2 LINC00632 MICAL1 MICAL3 RABIF RUSC2 SMARCC2 TOMM40L
Entrez ID		81876
HPRD ID		11469
Ensembl ID		ENSG00000174903
Uniprot IDs		Q9H0U4
PDB IDs		3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU 8ALK
Enriched GO Terms of Interacting Partners?		F-actin Monooxygenase Activity Small GTPase Binding Actin Filament Depolymerization Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen GDP-dissociation Inhibitor Activity Vesicle-mediated Transport Protein-containing Complex Disassembly Regulation Of Toll-like Receptor Signaling Pathway Midbody FAD Binding Protein Depolymerization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Transport Small GTPase-mediated Signal Transduction Actin Polymerization Or Depolymerization Golgi Vesicle Transport Monooxygenase Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Establishment Of Protein Localization Rab GDP-dissociation Inhibitor Activity Sulfur Oxidation Hippocampal Mossy Fiber Expansion Protein-containing Complex PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Intercellular Bridge Intracellular Signaling Cassette Post-Golgi Vesicle-mediated Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Rab-protein Geranylgeranyltransferase Complex Rab Geranylgeranyltransferase Activity
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