KRTAP1-1 and SEMA3B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP1-1	SEMA3B
Description		keratin associated protein 1-1	semaphorin 3B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Region Endoplasmic Reticulum Plasma Membrane Extracellular Matrix
	Molecular Function	Protein Binding	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process		Neural Crest Cell Migration Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Migration Negative Chemotaxis Chemorepulsion Of Axon Semaphorin-plexin Signaling Pathway
Pathways		Keratinization
Drugs
Diseases
GWAS			Obese vs. thin ( 30677029) Sleep duration (short sleep) ( 30846698) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		218 interacting genes: ADAM12 ADAMTSL3 ADAMTSL4 AGXT AKR7A3 ALDH3B1 ALPP AQP1 ASPSCR1 ATG9A BCAM C10orf62 C11orf87 C19orf38 CAMK2B CATIP CATSPER1 CD300LG CERK CHIC2 CHRD CHRNG CLDN2 CNNM3 CREB5 CRH CRY2 CSF1 CST2 CTRC CTSZ CYSLTR2 CYSRT1 DHRS1 DMRT3 DOCK2 DRD5 EFNA3 EMC7 FAM221A FAM76B FAM90A1 FARS2 FBXW5 FEZF1 FKBP1B FOXD4L3 FRS3 FZD10 GARIN6 GLP1R GLYAT GNE GRN GSTP1 GUCD1 HCK HEY2 HHEX HOXA1 HOXB5 HOXB9 HOXC8 HPCAL1 HSBP1 HSPA12B HYAL2 IFITM2 IGSF8 IL16 INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KRT20 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP13-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 LRFN4 LRRN4 MAGOHB MAPKBP1 MELTF MGAT5B MRGBP MRPL23 MT1B MXD3 MXI1 MYOM1 NECTIN2 NECTIN3 NMU NPDC1 NR1D2 NTM NUBP2 NUFIP2 OLFM2 OLIG3 OR14I1 OTX1 P2RX4 P2RY6 PCSK5 PDE9A PGAP6 PHLDA1 POU4F2 PRF1 PRKAB2 PRKAG1 PRPF31 PSMA1 PTK7 PTPMT1 PVR QPRT R3HDM2 RASD1 REM2 RNF111 RPS19BP1 RPS28 RPUSD3 RTN4RL1 SCARF1 SCNM1 SDC3 SEMA3B SHFL SLC23A1 SLC43A2 SLC68A1 SLC6A20 SLC7A11 SLIT1 SMARCE1 SMCP SMOC1 SNAI1 SNX18 SPACA9 SPRY1 STK16 TAPBPL TCEANC TFAP2D TGFB1 TLE5 TNP2 TSFM VASN VGLL3 VSTM4 WNT11 ZBTB48 ZBTB9 ZDHHC1 ZFTRAF1 ZNF124 ZNF330 ZNF408 ZNF414 ZNF417 ZNF439 ZNF440 ZNF446 ZNF491 ZNF497 ZNF524 ZNF581 ZNF587 ZNF648 ZNF669 ZNF696 ZNF786 ZNF837	23 interacting genes: BOLL CARD10 CREBBP CYSRT1 HSF2BP KPRP KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP5-9 MDFI NAA10 NBPF19 NOTCH2NLA NRP1 NRP2 PAK6 PICK1 RBPMS2 SEMA3A TRIP13
Entrez ID		81851	7869
HPRD ID		12304	03179
Ensembl ID		ENSG00000188581	ENSG00000012171
Uniprot IDs		Q07627	A0A0C4DGV8 B4DEK9 Q13214 Q6PI51
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Susceptibility To T Cell Mediated Cytotoxicity	Sympathetic Neuron Projection Guidance Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Sympathetic Neuron Projection Extension Intermediate Filament Branchiomotor Neuron Axon Guidance Facial Nerve Structural Organization Sympathetic Ganglion Development Axon Extension Involved In Axon Guidance Ganglion Development Vestibulocochlear Nerve Structural Organization Anatomical Structure Arrangement Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Neuron Projection Arborization Ventral Trunk Neural Crest Cell Migration Neuron Projection Extension Basal Dendrite Arborization Basal Dendrite Morphogenesis Motor Neuron Axon Guidance Trigeminal Ganglion Development Cranial Ganglion Development Trunk Neural Crest Cell Migration Developmental Cell Growth Semaphorin-plexin Signaling Pathway Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Developmental Growth Involved In Morphogenesis Axon Extension Vascular Endothelial Growth Factor Receptor Activity Female Meiosis I Hypothalamus Cell Migration Neural Crest Cell Migration Mesenchymal Cell Migration Axonogenesis Involved In Innervation N-terminal Protein Amino Acid Acetylation Dendrite Arborization Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Axon Extension Involved In Axon Guidance Sympathetic Nervous System Development Keratin Filament Identical Protein Binding Acetyltransferase Activity Tissue Development Vascular Endothelial Growth Factor Signaling Pathway Female Meiotic Nuclear Division Developmental Process Male Meiosis I Outflow Tract Septum Morphogenesis
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