GDPD5 and CLINT1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		GDPD5	CLINT1
Description		glycerophosphodiester phosphodiesterase domain containing 5	clathrin interactor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Growth Cone Cell Projection Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Protein Binding Phosphoric Diester Hydrolase Activity Glycerophosphodiester Phosphodiesterase Activity Hydrolase Activity Glycerophosphocholine Phosphodiesterase Activity	Protein Binding Phospholipid Binding Lipid Binding Clathrin Binding Cadherin Binding
	Biological Process	Lipid Metabolic Process Nervous System Development Positive Regulation Of Cell Differentiation Positive Regulation Of Neuron Differentiation	Endocytosis Clathrin Coat Assembly
Pathways		Glycerophospholipid catabolism	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Colorectal or endometrial cancer ( 26621817) Coronary artery disease ( 29212778) Height ( 31562340)	Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		5 interacting genes: CLINT1 KRTAP26-1 PEX5 PLSCR1 SIAH1	14 interacting genes: AP1G1 AP2A1 AP2B1 CALM1 CEBPA CLTC DNM1 EPS15 GDPD5 GGA1 GGA2 GGA3 JUN YWHAG
Entrez ID		81544	9685
HPRD ID		15159	06273
Ensembl ID		ENSG00000158555	ENSG00000113282
Uniprot IDs		Q8WTR4	A0A0S2Z4Y4 A0A0S2Z5H3 Q14677
PDB IDs			1XGW 2QY7 2V8S
Enriched GO Terms of Interacting Partners?		Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking	Clathrin-coated Pit Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Clathrin Coat Assembly Clathrin-coated Vesicle Vesicle-mediated Transport In Synapse Endocytosis Postsynaptic Neurotransmitter Receptor Internalization Presynaptic Endocytosis Postsynaptic Endocytic Zone Cytosolic Transport Golgi Vesicle Transport AP-2 Adaptor Complex Intracellular Protein Transport Establishment Of Protein Localization Receptor-mediated Endocytosis Import Into Cell Trans-Golgi Network Receptor Internalization Clathrin Adaptor Activity Endolysosome Membrane Establishment Of Localization In Cell Protein Transport Clathrin-coated Endocytic Vesicle Intracellular Transport Ubiquitin Binding Intracellular Protein Localization Membrane Coat Protein Localization To Cell Surface Clathrin-dependent Endocytosis Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport To The Plasma Membrane Negative Regulation Of Hyaluronan Biosynthetic Process Synaptic Vesicle Endocytosis Cellular Localization Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Of Coated Pit Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Protein-containing Complex Early Endosome Membrane Clathrin-coated Endocytic Vesicle Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Clathrin Adaptor Complex Endosomal Transport Golgi To Endosome Transport Small GTPase Binding Phosphatidylinositol Binding
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