DPF3 and ESRRA

Number of citations of the paper that reports this interaction (PMID 20400511)
4

Data Source:
BioGRID (pull down)

		DPF3	ESRRA
Gene Name		D4, zinc and double PHD fingers, family 3	estrogen-related receptor alpha
Image
Gene Ontology Annotations	Cellular Component	NBAF Complex	Nucleus Nucleoplasm Nucleolus Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Steroid Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nervous System Development Biological_process Chromatin Modification	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Gene Expression Intracellular Receptor Signaling Pathway Regulation Of Cell Proliferation Steroid Hormone Mediated Signaling Pathway Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cartilage Development
Pathways			PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Nuclear Receptor transcription pathway Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS			Crohn's disease ( 21102463)
Protein-Protein Interactions		5 interactors: ESRRA SMARCA2 SMARCA4 SMARCB1 SMARCD1	34 interactors: ADH5 ATXN1 DPF1 DPF2 DPF3 DUT EIF3I ESR1 ESRRG EXOSC6 FUS GTF2B HDAC8 KAT2B LYST MACF1 MAP2K5 NCOA1 NCOA3 NR0B1 NR0B2 NRIP1 NSD1 NXF1 PIAS4 PNRC2 PPARGC1A PRKCD PROX1 SIRT1 SMARCD3 SP1 SRC TNNI2
Entrez ID		8110	2101
HPRD ID		03395	07210
Ensembl ID		ENSG00000205683	ENSG00000173153
Uniprot IDs		B7Z276 F5H575 F8W7T1 Q92784	P11474 Q569H8
PDB IDs		2KWJ 2KWK 2KWN 2KWO	1XB7 2PJL 3D24 3K6P
Enriched GO Terms of Interacting Partners?		Nucleosome Disassembly Chromatin Remodeling Aortic Smooth Muscle Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation By Host Of Viral Transcription Chromatin Modification Nucleosome Organization Chromatin Assembly Or Disassembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Blastocyst Hatching Vascular Smooth Muscle Cell Differentiation Protein Complex Disassembly Positive Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Interaction With Symbiont Positive Regulation Of Viral Transcription Organelle Organization Smooth Muscle Cell Differentiation Positive Regulation Of Metabolic Process ATP-dependent Chromatin Remodeling Regulation Of Viral Transcription Positive Regulation Of Viral Process System Development Blastocyst Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Nitrogen Compound Metabolic Process Nervous System Development Negative Regulation Of Cell Growth Transcription, DNA-templated Regulation Of Viral Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Developmental Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Methylation On Cytosine Within A CG Sequence	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Receptor Signaling Pathway Biosynthetic Process Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Chromatin Modification Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Reproductive Structure Development Negative Regulation Of Cellular Metabolic Process Reproductive System Development Chromatin Organization Response To Hormone
Tagcloud ?			biogenesis constituent coregulated ctf1 dap3 elk1 elk4 exploring gabpa gtp hdap3 homoeostasis hox11 microarray mitochondrial nrf oncocytic pparg presenting publicly ribosome runx1 rxra silico tal1 ternary tumourigenesis tumours upregulated
Tagcloud (Difference) ?			biogenesis constituent coregulated ctf1 dap3 elk1 elk4 exploring gabpa gtp hdap3 homoeostasis hox11 microarray mitochondrial nrf oncocytic pparg presenting publicly ribosome runx1 rxra silico tal1 ternary tumourigenesis tumours upregulated
Tagcloud (Intersection) ?