IFT88 and MSRB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFT88	MSRB1
Description		intraflagellar transport 88	methionine sulfoxide reductase B1
Image		No pdb structure
GO Annotations	Cellular Component	Manchette Nucleolus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Microtubule Cytoskeleton Intraciliary Transport Particle B Motile Cilium Centriolar Satellite Ciliary Basal Body Sperm Flagellum Cell Projection Intercellular Bridge Mitotic Spindle Ciliary Tip Ciliary Base Non-motile Cilium Sperm Head-tail Coupling Apparatus	Nucleus Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton
	Molecular Function	Protein Binding Kinesin Binding	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity Metal Ion Binding
	Biological Process	Kidney Development Cell Projection Organization Response To Silicon Dioxide Intraciliary Anterograde Transport Intraciliary Transport Positive Regulation Of Cilium Assembly Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly	Immune System Process Actin Filament Polymerization Protein Repair Innate Immune Response
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Protein repair
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)	Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		14 interacting genes: CACNA1C CAPN7 CCDC120 DSCAM EEF2KMT EML2 FBXO7 HUNK ITPKB MSRB1 PRRC2A RPGR SMARCE1 VHL	6 interacting genes: CLU CYSRT1 IFT88 INCA1 TRIM27 VKORC1
Entrez ID		8100	51734
HPRD ID		09000	12095
Ensembl ID		ENSG00000032742	ENSG00000198736
Uniprot IDs		A0A140VJL7 B3KX42 Q13099	Q9NZV6
PDB IDs			3MAO
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Activation Of Membrane Attack Complex Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Inclusion Body Assembly Negative Regulation Of Complement-dependent Cytotoxicity Central Nervous System Myelin Maintenance Neurofibrillary Tangle Chromaffin Granule Regulation Of Neuronal Signal Transduction Positive Regulation Of Amyloid Fibril Formation Immune Complex Clearance Response To Silicon Dioxide Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Neurofibrillary Tangle Assembly
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