MSRB1

Description		methionine sulfoxide reductase B1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity Metal Ion Binding
	Biological Process	Immune System Process Actin Filament Polymerization Protein Repair Innate Immune Response
Pathways		Protein repair
Drugs
Diseases
GWAS		Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		6 interacting genes: CLU CYSRT1 IFT88 INCA1 TRIM27 VKORC1
Entrez ID		51734
HPRD ID		12095
Ensembl ID		ENSG00000198736
Uniprot IDs		Q9NZV6
PDB IDs		3MAO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Activation Of Membrane Attack Complex Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Inclusion Body Assembly Negative Regulation Of Complement-dependent Cytotoxicity Central Nervous System Myelin Maintenance Neurofibrillary Tangle Chromaffin Granule Regulation Of Neuronal Signal Transduction Positive Regulation Of Amyloid Fibril Formation Immune Complex Clearance Response To Silicon Dioxide Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Regulation Of Neurofibrillary Tangle Assembly
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