SLC35G2 and TMEM86B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC35G2	TMEM86B
Description		solute carrier family 35 member G2	transmembrane protein 86B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity D-lysine 5,6-aminomutase Activity
	Biological Process		Lipid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process
Pathways			Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Estimated glomerular filtration rate ( 31152163) Lymphocyte count ( 32888494) Neurociticism ( 29500382) Schizophrenia ( 25056061 29483656)	Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 28714469 33536424)
Interacting Genes		7 interacting genes: ACAP3 AQP6 FAM209A FCER1G SEMA3F SLC10A6 TMEM86B	106 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FFAR2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22
Entrez ID		80723	255043
HPRD ID		15532	14540
Ensembl ID		ENSG00000168917	ENSG00000180089
Uniprot IDs		Q8TBE7	Q8N661
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Nitrate Transmembrane Transport Carbon Dioxide Transmembrane Transport Positive Regulation Of Type I Hypersensitivity Mast Cell Apoptotic Process Serotonin Secretion Negative Regulation Of Mast Cell Apoptotic Process IgE Receptor Activity Positive Regulation Of Type IIa Hypersensitivity Serotonin Secretion By Platelet Positive Regulation Of Mast Cell Cytokine Production IgE Binding Regulation Of Mast Cell Apoptotic Process Organic Hydroxy Compound Transport Fc-gamma Receptor III Complex Fc-epsilon Receptor I Complex Positive Regulation Of Type III Hypersensitivity Ventral Trunk Neural Crest Cell Migration Sympathetic Neuron Projection Guidance Trunk Neural Crest Cell Migration D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Bile Acid:sodium Symporter Activity Sodium-dependent Organic Anion Transport Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Sympathetic Neuron Projection Extension Positive Regulation Of Hypersensitivity Interleukin-3-mediated Signaling Pathway Branchiomotor Neuron Axon Guidance Monoatomic Anion Channel Activity Renal Water Transport Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Mast Cell Activation Ammonium Channel Activity Facial Nerve Structural Organization Negative Regulation Of Axon Extension Involved In Axon Guidance Sympathetic Ganglion Development Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cell Migration Axon Extension Involved In Axon Guidance Neutrophil Activation Involved In Immune Response Serotonin Transport IgG Binding Positive Regulation Of Inflammatory Response To Antigenic Stimulus	Membrane SNAP Receptor Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Complex Protein Binding Membrane Fusion Mitochondrial Membrane Endomembrane System Plasma Membrane Organelle Localization By Membrane Tethering Membrane Organization Cellular Localization Vesicle Membrane Docking Vesicle Fusion Vesicle Docking Organelle Membrane Fusion SNARE Binding Golgi Vesicle Transport C-4 Methylsterol Oxidase Activity Sterol Biosynthetic Process Vesicle Organization Organelle Fusion Connexin Complex B Cell Receptor Complex Gap Junction Channel Activity Nuclear Inner Membrane Localization Within Membrane Gap Junction
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