TMEM86B and DNAJC30

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM86B	DNAJC30
Description		transmembrane protein 86B	DnaJ heat shock protein family (Hsp40) member C30
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Hydrolase Activity Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity D-lysine 5,6-aminomutase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 28714469 33536424)	Malaria ( 31844061)
Interacting Genes		106 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FFAR2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22	30 interacting genes: AQP6 BEST2 CALN1 CREB3 EBP EXOSC6 FAM209A FATE1 FBXO7 GPX8 JAGN1 KASH5 LMNA LRRC25 MGST2 MRM1 MSMO1 OPRL1 PEX12 REEP4 RNF170 S100B SIGLEC12 SLC10A4 SLC35H1 SLC51A SLC71A2 TMEM31 TMEM52B TMEM86B
Entrez ID		255043	84277
HPRD ID		14540	10303
Ensembl ID		ENSG00000180089	ENSG00000176410
Uniprot IDs		Q8N661	B3KSU4 Q96LL9
PDB IDs			2YUA
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Complex Protein Binding Membrane Fusion Mitochondrial Membrane Endomembrane System Plasma Membrane Organelle Localization By Membrane Tethering Membrane Organization Cellular Localization Vesicle Membrane Docking Vesicle Fusion Vesicle Docking Organelle Membrane Fusion SNARE Binding Golgi Vesicle Transport C-4 Methylsterol Oxidase Activity Sterol Biosynthetic Process Vesicle Organization Organelle Fusion Connexin Complex B Cell Receptor Complex Gap Junction Channel Activity Nuclear Inner Membrane Localization Within Membrane Gap Junction	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum
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