TMEM14A and SLC19A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM14A	SLC19A3
Description		transmembrane protein 14A	solute carrier family 19 member 3
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Thiamine Transmembrane Transporter Activity Vitamin Transmembrane Transporter Activity
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Thiamine Diphosphate Biosynthetic Process Thiamine Transport Pyridoxine Transport Thiamine-containing Compound Metabolic Process Vitamin Transport Transmembrane Transport Thiamine Transmembrane Transport
Pathways			Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)
Interacting Genes		39 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP FAM209A FKBP7 IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SAR1A SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC35H1 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18	15 interacting genes: ARLN C3orf38 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1
Entrez ID		28978	80704
HPRD ID		15522	07311
Ensembl ID		ENSG00000096092	ENSG00000135917
Uniprot IDs		Q9Y6G1	A0A2R8YHG5 Q9BZV2
PDB IDs		2LOO 2LOP	8S4U 8S5U 8S5W 8S5Z 8S61 8S62 8XV2 8XV5 8XV9 8Z7R 8Z7S 8Z7T 8Z7U 8Z7V 8Z7W 8Z7X 8Z7Y 9G5K
Enriched GO Terms of Interacting Partners?		Membrane Negative Regulation Of Apoptotic Process Neuregulin Receptor Activity Negative Regulation Of Programmed Cell Death Melatonin Receptor Activity Transmembrane Transport
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