TRIM45 and UBE2B

Number of citations of the paper that reports this interaction (PMID 24681954)
0

Data Source:
BioGRID (pull down)

		TRIM45	UBE2B
Gene Name		tripartite motif containing 45	ubiquitin-conjugating enzyme E2B
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intercellular Bridge	Chromatin Nuclear Chromatin XY Body Nucleus Replication Fork Cytoplasm Plasma Membrane HULC Complex
	Molecular Function	Zinc Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Bone Development	Protein Polyubiquitination Response To Hypoxia In Utero Embryonic Development DNA Repair Postreplication Repair Maintenance Of Chromatin Silencing Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Spermatogenesis Sperm Axoneme Assembly Response To UV Positive Regulation Of Reciprocal Meiotic Recombination Protein Ubiquitination Cellular Response To Insulin Stimulus Negative Regulation Of Histone Phosphorylation Histone H2A Ubiquitination Response To Drug Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of CAMP-mediated Signaling Protein Stabilization Chiasma Assembly Protein Autoubiquitination Canonical Wnt Signaling Pathway Histone Lysine Demethylation Synaptonemal Complex Organization Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3	19 interactors: BIRC2 CDKN1B CNOT4 CRMP1 CTNNB1 HIST2H2AC MED31 PCNA RAD18 RNF20 RNF40 TRIM45 UBA1 UBC UBR1 UBR2 UBR3 UBR5 UNC119
Entrez ID		80263	7320
HPRD ID		15562	01533
Ensembl ID		ENSG00000134253	ENSG00000119048
Uniprot IDs		Q9H8W5	P63146
PDB IDs		2DS4	1JAS 1NXA 2Y4W 2YB6 2YBF
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein K11-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K63-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Protein Metabolic Process Response To Hypoxia ISG15-protein Conjugation Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Chromosome Organization Cellular Macromolecule Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Pattern Recognition Receptor Signaling Pathway Protein Metabolic Process Innate Immune Response-activating Signal Transduction Regulation Of Cell Cycle Process Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Cellular Response To Stress Proteolysis Mitotic Spindle Assembly Checkpoint Regulation Of Innate Immune Response Histone Ubiquitination Spindle Assembly Checkpoint Regulation Of Cell Division Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Response To Leucine Proteolysis Histone Ubiquitination Cellular Protein Modification Process Regulation Of Protein K63-linked Ubiquitination Protein Polyubiquitination Response To Cadmium Ion Response To Leucine Histone H2B Ubiquitination Cellular Response To DNA Damage Stimulus Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Response To Amino Acid Cell Cycle Process Positive Regulation Of Canonical Wnt Signaling Pathway Cellular Protein Metabolic Process Histone Monoubiquitination Regulation Of Histone Modification Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Negative Regulation Of TOR Signaling Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Organonitrogen Compound Positive Regulation Of Histone Methylation Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Chromosome Organization Negative Regulation Of Protein Metabolic Process Protein Monoubiquitination Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays mrpl20 rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese wars2 zmym6
Tagcloud (Difference) ?		capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays mrpl20 rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese wars2 zmym6
Tagcloud (Intersection) ?