CEP290 and C9orf16

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP290	C9orf16
Gene Name		centrosomal protein 290kDa	chromosome 9 open reading frame 16
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytosol Membrane Photoreceptor Connecting Cilium Centriolar Satellite TCTN-B9D Complex Ciliary Basal Body Protein Complex	Cellular_component
	Molecular Function	Protein Binding Microtubule Minus-end Binding	Molecular_function
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Establishment Or Maintenance Of Cell Polarity Protein Transport Regulation Of CAMP Metabolic Process Hindbrain Development Otic Vesicle Formation Cilium Assembly Eye Photoreceptor Cell Development Positive Regulation Of Transcription, DNA-templated Pronephros Development Retina Development In Camera-type Eye Cilium Morphogenesis Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport	Biological_process
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: C9orf16 MAPK10	7 interactors: ATP6V1D ATP6V1E2 CEP290 IKBIP INPP1 KRT20 THAP11
Entrez ID		80184	79095
HPRD ID			12946
Ensembl ID		ENSG00000198707	ENSG00000171159
Uniprot IDs		O15078 Q05BJ6	Q9BUW7
PDB IDs
Enriched GO Terms of Interacting Partners?		JUN Phosphorylation	Transferrin Transport Phagosome Maturation Iron Ion Transport Cellular Iron Ion Homeostasis Interaction With Host Iron Ion Homeostasis Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Cilium Assembly Cilium Organization Cellular Response To Insulin Stimulus Cilium Morphogenesis Proton Transport Pronephros Development Cell Projection Assembly Response To Insulin Otic Vesicle Formation Cellular Response To Peptide Hormone Stimulus Otic Vesicle Morphogenesis Cellular Response To Peptide Protein Localization To Cilium Otic Vesicle Development Intermediate Filament Organization Cellular Metal Ion Homeostasis Protein Transport Cellular Cation Homeostasis Establishment Of Protein Localization Cellular Ion Homeostasis Response To Peptide Hormone Organelle Organization Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Organelle Assembly Response To Peptide Response To X-ray Cellular Chemical Homeostasis
Tagcloud ?		aplasia cerebellar cerebello cilia ciliopathy collecting cystic displays exploited giving gli3 hedgehog hh impairments implicate jbts joubert kidneys lef1 nephronophthisis newborn nphp nphp6 oculo purmorphamine spheroid tcf1 therapeutically vermis
Tagcloud (Difference) ?		aplasia cerebellar cerebello cilia ciliopathy collecting cystic displays exploited giving gli3 hedgehog hh impairments implicate jbts joubert kidneys lef1 nephronophthisis newborn nphp nphp6 oculo purmorphamine spheroid tcf1 therapeutically vermis
Tagcloud (Intersection) ?